decreased circulating interleukin-1 level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the amount in the blood of a soluble factor produced by monocytes, macrophages and other cells, which activates T-lymphocytes and potentiates their response to mitogens or antigens (Mammalian Phenotype Ontology, MP_0008592)
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2 gene mutations causing the decreased circulating interleukin-1 level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
IL1RN interleukin 1 receptor antagonist
IRAK4 interleukin-1 receptor-associated kinase 4