decreased circulating levels of thyroid hormone Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced concentration of hormones in the blood that are synthesized and secreted by the thyroid (Mammalian Phenotype Ontology, MP_0003351)
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37 gene mutations causing the decreased circulating levels of thyroid hormone phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARRDC3 arrestin domain containing 3
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CRYM crystallin, mu
CYBA cytochrome b-245, alpha polypeptide
DIO3 deiodinase, iodothyronine, type III
DUOX2 dual oxidase 2
EDN2 endothelin 2
FOXE1 forkhead box E1
FRK fyn-related Src family tyrosine kinase
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GHR growth hormone receptor
KLC2 kinesin light chain 2
LEPROT leptin receptor overlapping transcript
LHX3 LIM homeobox 3
MED1 mediator complex subunit 1
NCOR1 nuclear receptor corepressor 1
OAT ornithine aminotransferase
PAX8 paired box 8
PDYN prodynorphin
POMC proopiomelanocortin
RUNX2 runt-related transcription factor 2
SIRT1 sirtuin 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SSFA2 sperm specific antigen 2
TG thyroglobulin
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TPST2 tyrosylprotein sulfotransferase 2
TRH thyrotropin-releasing hormone
TRHR thyrotropin-releasing hormone receptor
TSHR thyroid stimulating hormone receptor
TTR transthyretin
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VGF VGF nerve growth factor inducible
WDR37 WD repeat domain 37