decreased circulating luteinizing hormone level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description lower than normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary (Mammalian Phenotype Ontology, MP_0002773)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002773
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Genes

18 gene mutations causing the decreased circulating luteinizing hormone level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CGA glycoprotein hormones, alpha polypeptide
CLOCK clock circadian regulator
CRTC1 CREB regulated transcription coactivator 1
FOXN1 forkhead box N1
GHR growth hormone receptor
GNRHR gonadotropin-releasing hormone receptor
IRS2 insulin receptor substrate 2
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
LATS1 large tumor suppressor kinase 1
LHCGR luteinizing hormone/choriogonadotropin receptor
NPEPPS aminopeptidase puromycin sensitive
NR1H3 nuclear receptor subfamily 1, group H, member 3
OTX2 orthodenticle homeobox 2
PGR progesterone receptor
PRL prolactin
SIRT1 sirtuin 1
SOD1 superoxide dismutase 1, soluble
Funding