decreased glucagon secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the production or release of this hormone secreted by the alpha cells of the islets of Langerhans; it normally plays a role in regulation of blood glucose concentration, ketone metabolism, and other biochemical and physiological processes (Mammalian Phenotype Ontology, MP_0002711)
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9 gene mutations causing the decreased glucagon secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CHRM3 cholinergic receptor, muscarinic 3
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
GPER1 G protein-coupled estrogen receptor 1
IL6 interleukin 6
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
NKX2-2 NK2 homeobox 2
PCSK2 proprotein convertase subtilisin/kexin type 2
SNAP25 synaptosomal-associated protein, 25kDa