decreased left ventricle systolic pressure Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description decrease in the pressure in the left ventricle as the heart contracts and pumps blood into the arteries (Mammalian Phenotype Ontology, MP_0003822)
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12 gene mutations causing the decreased left ventricle systolic pressure phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
DNM1L dynamin 1-like
FGF2 fibroblast growth factor 2 (basic)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
MAOA monoamine oxidase A
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
NRG1 neuregulin 1
PDLIM5 PDZ and LIM domain 5
TIMP3 TIMP metallopeptidase inhibitor 3
TNNT2 troponin T type 2 (cardiac)
VEGFA vascular endothelial growth factor A