decreased liver weight Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced average weight of the bile-secreting exocrine gland (Mammalian Phenotype Ontology, MP_0003402)
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68 gene mutations causing the decreased liver weight phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
AIP aryl hydrocarbon receptor interacting protein
ARF6 ADP-ribosylation factor 6
ATR ATR serine/threonine kinase
BAG3 BCL2-associated athanogene 3
BMP5 bone morphogenetic protein 5
CCNG1 cyclin G1
CES1 carboxylesterase 1
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CRBN cereblon
CXCL14 chemokine (C-X-C motif) ligand 14
DEDD death effector domain containing
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF6 eukaryotic translation initiation factor 6
FABP2 fatty acid binding protein 2, intestinal
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP6 fatty acid binding protein 6, ileal
G0S2 G0/G1 switch 2
GAB1 GRB2-associated binding protein 1
GHR growth hormone receptor
GNMT glycine N-methyltransferase
GPER1 G protein-coupled estrogen receptor 1
GRB14 growth factor receptor-bound protein 14
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
JUND jun D proto-oncogene
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KL klotho
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MAPK6 mitogen-activated protein kinase 6
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBD5 methyl-CpG binding domain protein 5
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MSTN myostatin
NCOA3 nuclear receptor coactivator 3
NEGR1 neuronal growth regulator 1
NFE2L2 nuclear factor, erythroid 2-like 2
PLA2G1B phospholipase A2, group IB (pancreas)
PNLIP pancreatic lipase
PRL prolactin
PSAP prosaposin
PTN pleiotrophin
RCAN2 regulator of calcineurin 2
SELENBP1 selenium binding protein 1
SENP1 SUMO1/sentrin specific peptidase 1
SERTAD2 SERTA domain containing 2
SIK3 SIK family kinase 3
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SNORD50A small nucleolar RNA, C/D box 50A
SNORD50B small nucleolar RNA, C/D box 50B
SRA1 steroid receptor RNA activator 1
STARD10 StAR-related lipid transfer (START) domain containing 10
STARD4 StAR-related lipid transfer (START) domain containing 4
THRA thyroid hormone receptor, alpha
TKT transketolase
TP53 tumor protein p53
WWOX WW domain containing oxidoreductase
XIRP2 xin actin binding repeat containing 2