decreased oligodendrocyte number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of cells of the central nervous system that form the insulating myelin sheath of axons in the CNS (Mammalian Phenotype Ontology, MP_0009808)
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13 gene mutations causing the decreased oligodendrocyte number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
GALC galactosylceramidase
KLK6 kallikrein-related peptidase 6
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
NKX2-2 NK2 homeobox 2
NOS2 nitric oxide synthase 2, inducible
NRG1 neuregulin 1
PLP1 proteolipid protein 1
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PTPRC protein tyrosine phosphatase, receptor type, C
SOX10 SRY (sex determining region Y)-box 10
TERT telomerase reverse transcriptase
ZNF24 zinc finger protein 24