decreased primordial ovarian follicle number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description fewer than normal numbers of the ovarian follicle in which the primary oocyte is surrounded by a single layer of flattened follicular cells; primordial follicles are indiscernible to the naked eye and develop to primary, secondary, and finally mature vesicular follicles (Mammalian Phenotype Ontology, MP_0011121)
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6 gene mutations causing the decreased primordial ovarian follicle number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ESR1 estrogen receptor 1
LIN28A lin-28 homolog A (C. elegans)
MCM9 minichromosome maintenance complex component 9
RAD21L1 RAD21-like 1 (S. pombe)
RSPO1 R-spondin 1
ZC3HC1 zinc finger, C3HC-type containing 1