decreased prostaglandin level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the amount in the body of any of a class of mediators with effects of vasodilation, vasoconstriction, and smooth muscle stimulation (Mammalian Phenotype Ontology, MP_0009815)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009815
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Genes

13 gene mutations causing the decreased prostaglandin level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
LEPR leptin receptor
LPAR3 lysophosphatidic acid receptor 3
NOS3 nitric oxide synthase 3 (endothelial cell)
PTGDR2 prostaglandin D2 receptor 2
PTGES prostaglandin E synthase
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
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