decreased secondary ovarian follicle number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description fewer than normal numbers of the ovarian follicle in which the primary oocyte attains its full size and is surrounded by an extracellular glycoprotein layer (zona pellucida) that separates it from a peripheral layer of follicular cells permeated by one or more fluid-filled antra; the primary oocyte occupies the cumulus oophorus while the theca of the follicle develops into internal and external layers (Mammalian Phenotype Ontology, MP_0011129)
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4 gene mutations causing the decreased secondary ovarian follicle number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CSF1 colony stimulating factor 1 (macrophage)
MCM8 minichromosome maintenance complex component 8
SGPL1 sphingosine-1-phosphate lyase 1
SRY sex determining region Y