decreased sensitivity to xenobiotic induced morbidity/mortality Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the amount of a foreign compound required to cause death or diseased state (Mammalian Phenotype Ontology, MP_0009767)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009767
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Genes

30 gene mutations causing the decreased sensitivity to xenobiotic induced morbidity/mortality phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACE angiotensin I converting enzyme
AHR aryl hydrocarbon receptor
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
CASP4 caspase 4, apoptosis-related cysteine peptidase
CAT catalase
CCL13 chemokine (C-C motif) ligand 13
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CREB3L3 cAMP responsive element binding protein 3-like 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DNASE1 deoxyribonuclease I
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCMR Fc fragment of IgM receptor
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
IL33 interleukin 33
INSR insulin receptor
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MMP9 matrix metallopeptidase 9
NPY1R neuropeptide Y receptor Y1
OPRM1 opioid receptor, mu 1
PELI1 pellino E3 ubiquitin protein ligase 1
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SOSTDC1 sclerostin domain containing 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A