decreased susceptibility to bacterial infection induced morbidity/mortality Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria (Mammalian Phenotype Ontology, MP_0009789)
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31 gene mutations causing the decreased susceptibility to bacterial infection induced morbidity/mortality phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ANTXR2 anthrax toxin receptor 2
APCS amyloid P component, serum
CASP12 caspase 12 (gene/pseudogene)
CCR1 chemokine (C-C motif) receptor 1
CD14 CD14 molecule
CD47 CD47 molecule
CTSG cathepsin G
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR2 chemokine (C-X-C motif) receptor 2
CYLD cylindromatosis (turban tumor syndrome)
ELANE elastase, neutrophil expressed
FCMR Fc fragment of IgM receptor
GUCY2C guanylate cyclase 2C
ICAM1 intercellular adhesion molecule 1
IL15 interleukin 15
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
OTUD7B OTU deubiquitinase 7B
PGLYRP2 peptidoglycan recognition protein 2
PILRB paired immunoglobin-like type 2 receptor beta
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAG2 recombination activating gene 2
S100A9 S100 calcium binding protein A9
SDC1 syndecan 1
SPP1 secreted phosphoprotein 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TERF2IP telomeric repeat binding factor 2, interacting protein
TLR2 toll-like receptor 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VTCN1 V-set domain containing T cell activation inhibitor 1