decreased susceptibility to induced choroidal neovascularization Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction or absence of growth of new, abnormal blood vessels that originate in the choroid through a break in the Bruch membrane into the sub-retinal pigment epithelium or subretinal space and may result in visual loss as a result of chemical or mechanical manipulation (e.g. laser-induced trauma) (Mammalian Phenotype Ontology, MP_0003434)
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9 gene mutations causing the decreased susceptibility to induced choroidal neovascularization phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ICAM1 intercellular adhesion molecule 1
IL10 interleukin 10
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLG plasminogen