decreased susceptibility to induction of seizure by inducing agent Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description higher threshold to induction of seizure activity response by an agent that normally can induce uncontrolled electrical activity in the brain, producing a physical convulsion and/or minor change in physical behavior (Mammalian Phenotype Ontology, MP_0012348)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012348
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Genes

26 gene mutations causing the decreased susceptibility to induction of seizure by inducing agent phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AKAP5 A kinase (PRKA) anchor protein 5
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CKB creatine kinase, brain
CLCN3 chloride channel, voltage-sensitive 3
FGF22 fibroblast growth factor 22
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRM5 glutamate receptor, metabotropic 5
JUN jun proto-oncogene
MAPK10 mitogen-activated protein kinase 10
MAPT microtubule-associated protein tau
NPY neuropeptide Y
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
PANX1 pannexin 1
PPP1R9B protein phosphatase 1, regulatory subunit 9B
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SEZ6 seizure related 6 homolog (mouse)
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
TRIM3 tripartite motif containing 3
TRPC5 transient receptor potential cation channel, subfamily C, member 5
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