decreased susceptibility to xenobiotic induced morbidity/mortality Gene Set

Dataset MGI Mouse Phenotype Associations 2023
Category disease or phenotype associations
Type phenotype
Description increase in the amount of a compound foreign to living organisms required to cause death or diseased state (Medical Subject Headings)
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Genes

37 gene mutations causing the decreased susceptibility to xenobiotic induced morbidity/mortality phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACE angiotensin I converting enzyme
AHR aryl hydrocarbon receptor
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
BABAM1 BRISC and BRCA1 A complex member 1
CASP5 caspase 5, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CREB3L3 cAMP responsive element binding protein 3-like 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DNASE1 deoxyribonuclease I
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCMR Fc fragment of IgM receptor
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
IL33 interleukin 33
INSR insulin receptor
KDM1A lysine (K)-specific demethylase 1A
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MGST2 microsomal glutathione S-transferase 2
MMP9 matrix metallopeptidase 9
MTDH metadherin
NPY1R neuropeptide Y receptor Y1
OPRM1 opioid receptor, mu 1
PELI1 pellino E3 ubiquitin protein ligase 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SOSTDC1 sclerostin domain containing 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
ZDHHC9 zinc finger, DHHC-type containing 9