decreased thymus weight Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the average weight of the primary lymphoid organ that is required for maturation of T cells (Mammalian Phenotype Ontology, MP_0004956)
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27 gene mutations causing the decreased thymus weight phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AFF1 AF4/FMR2 family, member 1
ATR ATR serine/threonine kinase
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
COL10A1 collagen, type X, alpha 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAD1 defender against cell death 1
DCLRE1C DNA cross-link repair 1C
DFNB31 deafness, autosomal recessive 31
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ESR1 estrogen receptor 1
HR hair growth associated
IL7 interleukin 7
KAT6A K(lysine) acetyltransferase 6A
LIG4 ligase IV, DNA, ATP-dependent
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
PFDN1 prefoldin subunit 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RORC RAR-related orphan receptor C
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TTC7A tetratricopeptide repeat domain 7A
WWOX WW domain containing oxidoreductase