decreased transitional stage t1 b cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of a type of transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen; this cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative (Mammalian Phenotype Ontology, MP_0009923)
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8 gene mutations causing the decreased transitional stage t1 b cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATP11C ATPase, class VI, type 11C
BCL3 B-cell CLL/lymphoma 3
CD22 CD22 molecule
HAX1 HCLS1 associated protein X-1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
SPNS2 spinster homolog 2 (Drosophila)
SYK spleen tyrosine kinase