decreased transitional stage t3 b cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of a type of a transitional stage B cell that expresses surface IgM and IgD, and CD62L; it is an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, and CD62L-positive (Mammalian Phenotype Ontology, MP_0010228)
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2 gene mutations causing the decreased transitional stage t3 b cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATP11C ATPase, class VI, type 11C
SPPL2A signal peptide peptidase like 2A