defense response to Gram-positive bacterium Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism. (Gene Ontology, GO_0050830)
External Link http://amigo.geneontology.org/amigo/term/GO:0050830
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Genes

99 genes participating in the defense response to Gram-positive bacterium biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADM adrenomedullin
ANG angiogenin, ribonuclease, RNase A family, 5
APP amyloid beta (A4) precursor protein
B2M beta-2-microglobulin
CALCA calcitonin-related polypeptide alpha
CASP4 caspase 4, apoptosis-related cysteine peptidase
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHGA chromogranin A
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CSRP1 cysteine and glycine-rich protein 1
CTSG cathepsin G
DCD dermcidin
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
DEFA4 defensin, alpha 4, corticostatin
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFA6 defensin, alpha 6, Paneth cell-specific
DEFB1 defensin, beta 1
DEFB103A defensin, beta 103A
DEFB104A defensin, beta 104A
DEFB106A defensin, beta 106A
DEFB107A defensin, beta 107A
DEFB114 defensin, beta 114
DEFB118 defensin, beta 118
DEFB119 defensin, beta 119
DEFB128 defensin, beta 128
DEFB136 defensin, beta 136
DEFB4A defensin, beta 4A
DMBT1 deleted in malignant brain tumors 1
DROSHA drosha, ribonuclease type III
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGR FGR proto-oncogene, Src family tyrosine kinase
GBP2 guanylate binding protein 2, interferon-inducible
GBP4 guanylate binding protein 4
GBP6 guanylate binding protein family, member 6
GBP7 guanylate binding protein 7
GPR15LG G protein-coupled receptor 15 ligand
GSDMD gasdermin D
H2BC11 H2B clustered histone 11
H2BC12 H2B clustered histone 12
H2BC12L H2B clustered histone 12 like
H2BC21 H2B clustered histone 21
H2BC4 H2B clustered histone 4
HAMP hepcidin antimicrobial peptide
HLA-A major histocompatibility complex, class I, A
HLA-E major histocompatibility complex, class I, E
HMGB2 high mobility group box 2
IL12A interleukin 12A
IL18 interleukin 18
IL1B interleukin 1, beta
IL6 interleukin 6
IL6R interleukin 6 receptor
KRT6A keratin 6A, type II
LALBA lactalbumin, alpha-
LBP lipopolysaccharide binding protein
LCE3A late cornified envelope 3A
LCE3B late cornified envelope 3B
LCE3C late cornified envelope 3C
LTF lactotransferrin
LYG1 lysozyme G-like 1
LYG2 lysozyme G-like 2
LYZ lysozyme
MBL2 mannose-binding lectin (protein C) 2, soluble
MPEG1 macrophage expressed 1
MYD88 myeloid differentiation primary response 88
NLRP6 NLR family, pyrin domain containing 6
NPY neuropeptide Y
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PNKD paroxysmal nonkinesigenic dyskinesia
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
REG3G regenerating islet-derived 3 gamma
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RNASE11 ribonuclease, RNase A family, 11 (non-active)
RNASE12 ribonuclease, RNase A family, 12 (non-active)
RNASE13 ribonuclease, RNase A family, 13 (non-active)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RNASE4 ribonuclease, RNase A family, 4
RNASE6 ribonuclease, RNase A family, k6
RNASE7 ribonuclease, RNase A family, 7
RNASE8 ribonuclease, RNase A family, 8
RNASE9 ribonuclease, RNase A family, 9 (non-active)
ROMO1 reactive oxygen species modulator 1
RPL39 ribosomal protein L39
SPRR2A small proline-rich protein 2A
STAB2 stabilin 2
TAC1 tachykinin, precursor 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR2 toll-like receptor 2
TNFRSF14 tumor necrosis factor receptor superfamily, member 14