deferoxamine-3760 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the deferoxamine-3760 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
ACTC1 actin, alpha, cardiac muscle 1
ADAM8 ADAM metallopeptidase domain 8
ADCY2 adenylate cyclase 2 (brain)
ADGRE3 adhesion G protein-coupled receptor E3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKAP6 A kinase (PRKA) anchor protein 6
ALLC allantoicase
ALOXE3 arachidonate lipoxygenase 3
ANGPTL4 angiopoietin-like 4
ANKH ANKH inorganic pyrophosphate transport regulator
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BBC3 BCL2 binding component 3
BCAM basal cell adhesion molecule (Lutheran blood group)
BMP6 bone morphogenetic protein 6
BTNL3 butyrophilin-like 3
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CD22 CD22 molecule
CDH8 cadherin 8, type 2
CDKL3 cyclin-dependent kinase-like 3
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHI3L2 chitinase 3-like 2
CLEC4E C-type lectin domain family 4, member E
CNPY4 canopy FGF signaling regulator 4
COL17A1 collagen, type XVII, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
CRP C-reactive protein, pentraxin-related
CRTC1 CREB regulated transcription coactivator 1
CYSLTR2 cysteinyl leukotriene receptor 2
CYTH1 cytohesin 1
DGCR14 DiGeorge syndrome critical region gene 14
DOCK5 dedicator of cytokinesis 5
DRICH1 aspartate-rich 1
DTNB dystrobrevin, beta
DUOX2 dual oxidase 2
EDA ectodysplasin A
EGFL7 EGF-like-domain, multiple 7
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP6 fatty acid binding protein 6, ileal
FRMD4B FERM domain containing 4B
FRMD8 FERM domain containing 8
GRM8 glutamate receptor, metabotropic 8
GUCA1B guanylate cyclase activator 1B (retina)
HDC histidine decarboxylase
HFE hemochromatosis
HIST1H3A histone cluster 1, H3a
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
IL5RA interleukin 5 receptor, alpha
ITGA8 integrin, alpha 8
KLHL25 kelch-like family member 25
KLK13 kallikrein-related peptidase 13
LCAT lecithin-cholesterol acyltransferase
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MFAP2 microfibrillar-associated protein 2
MFAP3L microfibrillar-associated protein 3-like
MON2 MON2 homolog (S. cerevisiae)
MPPE1 metallophosphoesterase 1
MYOM1 myomesin 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NF1 neurofibromin 1
NME8 NME/NM23 family member 8
NPHP4 nephronophthisis 4
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OLFML2B olfactomedin-like 2B
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PBX1 pre-B-cell leukemia homeobox 1
PBX2 pre-B-cell leukemia homeobox 2
PDZK1IP1 PDZK1 interacting protein 1
PGAP3 post-GPI attachment to proteins 3
PHF7 PHD finger protein 7
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G3 phospholipase A2, group III
PLP1 proteolipid protein 1
PNLIPRP2 pancreatic lipase-related protein 2
POU2F2 POU class 2 homeobox 2
PRB1 proline-rich protein BstNI subfamily 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSG1 pregnancy specific beta-1-glycoprotein 1
SALL1 spalt-like transcription factor 1
SKIL SKI-like proto-oncogene
SLAMF7 SLAM family member 7
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SPATA6 spermatogenesis associated 6
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SYN3 synapsin III
SYNGR3 synaptogyrin 3
SYP synaptophysin
TADA3 transcriptional adaptor 3
TBCD tubulin folding cofactor D
TEX14 testis expressed 14
TRIM3 tripartite motif containing 3
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZBTB7A zinc finger and BTB domain containing 7A
ZC3H7B zinc finger CCCH-type containing 7B
ZNF516 zinc finger protein 516

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ACADSB acyl-CoA dehydrogenase, short/branched chain
ANKRD36 ankyrin repeat domain 36
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARRB2 arrestin, beta 2
BDKRB1 bradykinin receptor B1
BMP4 bone morphogenetic protein 4
C14ORF93 chromosome 14 open reading frame 93
C17ORF80 chromosome 17 open reading frame 80
CAMKMT calmodulin-lysine N-methyltransferase
CCDC71 coiled-coil domain containing 71
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CHM choroideremia (Rab escort protein 1)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CINP cyclin-dependent kinase 2 interacting protein
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COBL cordon-bleu WH2 repeat protein
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNAL4 dynein, axonemal, light chain 4
DSC2 desmocollin 2
EGR2 early growth response 2
ELSPBP1 epididymal sperm binding protein 1
ERF Ets2 repressor factor
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM160B2 family with sequence similarity 160, member B2
FAM186A family with sequence similarity 186, member A
FGL1 fibrinogen-like 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H1D histone cluster 1, H1d
HOXC11 homeobox C11
INO80D INO80 complex subunit D
KDM8 lysine (K)-specific demethylase 8
KIAA0895 KIAA0895
KLHL36 kelch-like family member 36
LIFR leukemia inhibitory factor receptor alpha
LOC100127972 uncharacterized LOC100127972
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC729164 hCG1732469
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LY86 lymphocyte antigen 86
MAN2C1 mannosidase, alpha, class 2C, member 1
MMP3 matrix metallopeptidase 3
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOD1 nucleotide-binding oligomerization domain containing 1
NT5M 5',3'-nucleotidase, mitochondrial
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGIN1 oxidative stress induced growth inhibitor 1
PALMD palmdelphin
PGP phosphoglycolate phosphatase
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PRPH peripherin
PRSS53 protease, serine, 53
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RNF39 ring finger protein 39
S1PR1 sphingosine-1-phosphate receptor 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SH2D2A SH2 domain containing 2A
SLC22A14 solute carrier family 22, member 14
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLMO1 slowmo homolog 1 (Drosophila)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOD3 superoxide dismutase 3, extracellular
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STARD3 StAR-related lipid transfer (START) domain containing 3
SUSD4 sushi domain containing 4
TAOK1 TAO kinase 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIGD6 tigger transposable element derived 6
TMEM8B transmembrane protein 8B
TPCN1 two pore segment channel 1
TRAC T cell receptor alpha constant
TRIM25 tripartite motif containing 25
TSPAN2 tetraspanin 2
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
TUBG2 tubulin, gamma 2
UBQLN4 ubiquilin 4
USP19 ubiquitin specific peptidase 19
VGLL3 vestigial-like family member 3
WFDC2 WAP four-disulfide core domain 2
WT1-AS WT1 antisense RNA
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZNF222 zinc finger protein 222
ZNF528 zinc finger protein 528
ZNF767P zinc finger family member 767, pseudogene