deferoxamine-3842 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the deferoxamine-3842 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK4 aarF domain containing kinase 4
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AHI1 Abelson helper integration site 1
AJAP1 adherens junctions associated protein 1
ALDOB aldolase B, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
ANGEL2 angel homolog 2 (Drosophila)
ANXA2P1 annexin A2 pseudogene 1
APOC1 apolipoprotein C-I
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG10 autophagy related 10
ATN1 atrophin 1
BEGAIN brain-enriched guanylate kinase-associated
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CA5B carbonic anhydrase VB, mitochondrial
CD1E CD1e molecule
CD2 CD2 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CDA cytidine deaminase
CFHR4 complement factor H-related 4
CLEC4M C-type lectin domain family 4, member M
CLTB clathrin, light chain B
COL4A2 collagen, type IV, alpha 2
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTNS cystinosin, lysosomal cystine transporter
CYLD cylindromatosis (turban tumor syndrome)
DGCR8 DGCR8 microprocessor complex subunit
DUSP6 dual specificity phosphatase 6
EPHB2 EPH receptor B2
FAM120C family with sequence similarity 120C
FKRP fukutin related protein
FN1 fibronectin 1
GIF gastric intrinsic factor (vitamin B synthesis)
GPR182 G protein-coupled receptor 182
GRM3 glutamate receptor, metabotropic 3
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAND1 heart and neural crest derivatives expressed 1
HIST1H1E histone cluster 1, H1e
HOXA1 homeobox A1
HOXA4 homeobox A4
HRASLS2 HRAS-like suppressor 2
IFITM1 interferon induced transmembrane protein 1
IFT27 intraflagellar transport 27
IL1RN interleukin 1 receptor antagonist
IMPG2 interphotoreceptor matrix proteoglycan 2
KIAA0754 KIAA0754
LGALS9 lectin, galactoside-binding, soluble, 9
MAN1C1 mannosidase, alpha, class 1C, member 1
MCM3AP minichromosome maintenance complex component 3 associated protein
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MEF2C myocyte enhancer factor 2C
MEF2D myocyte enhancer factor 2D
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MRAS muscle RAS oncogene homolog
MRC2 mannose receptor, C type 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR8 myotubularin related protein 8
MYRF myelin regulatory factor
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NNAT neuronatin
NOL12 nucleolar protein 12
NUP54 nucleoporin 54kDa
OMG oligodendrocyte myelin glycoprotein
ONECUT1 one cut homeobox 1
PAIP2B poly(A) binding protein interacting protein 2B
PDLIM4 PDZ and LIM domain 4
POM121 POM121 transmembrane nucleoporin
POPDC3 popeye domain containing 3
PXDC1 PX domain containing 1
RBM34 RNA binding motif protein 34
RUFY3 RUN and FYVE domain containing 3
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SAYSD1 SAYSVFN motif domain containing 1
SCN4A sodium channel, voltage gated, type IV alpha subunit
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SIRT4 sirtuin 4
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SPEG SPEG complex locus
SPHK2 sphingosine kinase 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TDRKH tudor and KH domain containing
TEX15 testis expressed 15
TICAM1 toll-like receptor adaptor molecule 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TSC2 tuberous sclerosis 2
TSC22D2 TSC22 domain family, member 2
TSKS testis-specific serine kinase substrate
TULP2 tubby like protein 2
USP20 ubiquitin specific peptidase 20
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDR78 WD repeat domain 78
WNT16 wingless-type MMTV integration site family, member 16
WSCD1 WSC domain containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF197 zinc finger protein 197
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADCY7 adenylate cyclase 7
ADTRP androgen-dependent TFPI-regulating protein
AKAP12 A kinase (PRKA) anchor protein 12
ASIC3 acid sensing (proton gated) ion channel 3
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BIRC7 baculoviral IAP repeat containing 7
C4BPA complement component 4 binding protein, alpha
C8ORF60 chromosome 8 open reading frame 60
CAMK1 calcium/calmodulin-dependent protein kinase I
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC71 coiled-coil domain containing 71
CDK6 cyclin-dependent kinase 6
CHM choroideremia (Rab escort protein 1)
CLASRP CLK4-associating serine/arginine rich protein
CTC1 CTS telomere maintenance complex component 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAPK3 death-associated protein kinase 3
DNM1 dynamin 1
DOC2A double C2-like domains, alpha
DUSP13 dual specificity phosphatase 13
ELSPBP1 epididymal sperm binding protein 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERCC4 excision repair cross-complementation group 4
EXD3 exonuclease 3'-5' domain containing 3
FAM155A family with sequence similarity 155, member A
FBXL2 F-box and leucine-rich repeat protein 2
FGF4 fibroblast growth factor 4
FILIP1L filamin A interacting protein 1-like
FKBP10 FK506 binding protein 10, 65 kDa
FLJ11710 uncharacterized protein FLJ11710
FMOD fibromodulin
G6PD glucose-6-phosphate dehydrogenase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLB1L galactosidase, beta 1-like
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTA4 glutathione S-transferase alpha 4
GTF2I general transcription factor IIi
HIST1H3E histone cluster 1, H3e
IFNA14 interferon, alpha 14
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LARP6 La ribonucleoprotein domain family, member 6
LHX1 LIM homeobox 1
LHX6 LIM homeobox 6
LIF leukemia inhibitory factor
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN1 mucolipin 1
MYO1E myosin IE
NCALD neurocalcin delta
NDE1 nudE neurodevelopment protein 1
NPM3 nucleophosmin/nucleoplasmin 3
NXPH4 neurexophilin 4
PCDH17 protocadherin 17
PEX26 peroxisomal biogenesis factor 26
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PPT2 palmitoyl-protein thioesterase 2
RAB36 RAB36, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF146 ring finger protein 146
RNF25 ring finger protein 25
RPGRIP1L RPGRIP1-like
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SPIDR scaffolding protein involved in DNA repair
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STON1 stonin 1
STRN striatin, calmodulin binding protein
TAOK1 TAO kinase 1
TBC1D2 TBC1 domain family, member 2
TCTN2 tectonic family member 2
TEX40 testis expressed 40
TMEM120B transmembrane protein 120B
TONSL tonsoku-like, DNA repair protein
TOR4A torsin family 4, member A
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TSC22D4 TSC22 domain family, member 4
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
TYRP1 tyrosinase-related protein 1
UPP1 uridine phosphorylase 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB33 zinc finger and BTB domain containing 33
ZFHX3 zinc finger homeobox 3
ZFP30 ZFP30 zinc finger protein
ZNF358 zinc finger protein 358
ZNF484 zinc finger protein 484
ZNF551 zinc finger protein 551
ZNF747 zinc finger protein 747