| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the deferoxamine-4317 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| ACVR1B | activin A receptor, type IB |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ANGPTL4 | angiopoietin-like 4 |
| ANKRD26 | ankyrin repeat domain 26 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP13A3 | ATPase type 13A3 |
| BCL2L1 | BCL2-like 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD52 | CD52 molecule |
| CD82 | CD82 molecule |
| CFH | complement factor H |
| CHAT | choline O-acetyltransferase |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COL6A1 | collagen, type VI, alpha 1 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DGCR14 | DiGeorge syndrome critical region gene 14 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EFNA3 | ephrin-A3 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBXO41 | F-box protein 41 |
| FN1 | fibronectin 1 |
| GLRA3 | glycine receptor, alpha 3 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GTPBP1 | GTP binding protein 1 |
| HSF1 | heat shock transcription factor 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGB4 | integrin, beta 4 |
| JAK3 | Janus kinase 3 |
| JUND | jun D proto-oncogene |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KITLG | KIT ligand |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAT2 | linker for activation of T cells family, member 2 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| LMAN1 | lectin, mannose-binding, 1 |
| LOC100294391 | uncharacterized LOC100294391 |
| LOC157562 | uncharacterized LOC157562 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LTB4R | leukotriene B4 receptor |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MCL1 | myeloid cell leukemia 1 |
| MED16 | mediator complex subunit 16 |
| MFN2 | mitofusin 2 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| NEBL | nebulette |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NMBR | neuromedin B receptor |
| NPTX2 | neuronal pentraxin II |
| PAPOLG | poly(A) polymerase gamma |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PCDH9 | protocadherin 9 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PIAS2 | protein inhibitor of activated STAT, 2 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PRKCA | protein kinase C, alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PXN | paxillin |
| PYY | peptide YY |
| RAB35 | RAB35, member RAS oncogene family |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RXRB | retinoid X receptor, beta |
| SARDH | sarcosine dehydrogenase |
| SCN1A | sodium channel, voltage gated, type I alpha subunit |
| SIRPA | signal-regulatory protein alpha |
| SLC17A2 | solute carrier family 17, member 2 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPPL2B | signal peptide peptidase like 2B |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRPR | signal recognition particle receptor (docking protein) |
| TACR1 | tachykinin receptor 1 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TNPO2 | transportin 2 |
| TRIM25 | tripartite motif containing 25 |
| TUBA3C | tubulin, alpha 3c |
| UST | uronyl-2-sulfotransferase |
| VARS | valyl-tRNA synthetase |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACVR2B | activin A receptor, type IIB |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BEX1 | brain expressed, X-linked 1 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLSPN | claspin |
| CRY2 | cryptochrome circadian clock 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DBF4B | DBF4 zinc finger B |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| ECM1 | extracellular matrix protein 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| FBRS | fibrosin |
| FBXO2 | F-box protein 2 |
| FGL1 | fibrinogen-like 1 |
| FLCN | folliculin |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR3 | G protein-coupled receptor 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GTPBP6 | GTP binding protein 6 (putative) |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4C | histone cluster 1, H4c |
| LOC257152 | uncharacterized LOC257152 |
| LRRC61 | leucine rich repeat containing 61 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MED18 | mediator complex subunit 18 |
| MMRN2 | multimerin 2 |
| MTA2 | metastasis associated 1 family, member 2 |
| MYOZ3 | myozenin 3 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NDP | Norrie disease (pseudoglioma) |
| NKX3-2 | NK3 homeobox 2 |
| NME5 | NME/NM23 family member 5 |
| NOL10 | nucleolar protein 10 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PDZK1 | PDZ domain containing 1 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRSS53 | protease, serine, 53 |
| PTK6 | protein tyrosine kinase 6 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RIN1 | Ras and Rab interactor 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SH2D2A | SH2 domain containing 2A |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STRA6 | stimulated by retinoic acid 6 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TEP1 | telomerase-associated protein 1 |
| TMEM19 | transmembrane protein 19 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAIP | TRAF interacting protein |
| TRIM16 | tripartite motif containing 16 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TTC30A | tetratricopeptide repeat domain 30A |
| USP20 | ubiquitin specific peptidase 20 |
| VASH2 | vasohibin 2 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR76 | WD repeat domain 76 |
| XYLT2 | xylosyltransferase II |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF219 | zinc finger protein 219 |
| ZNF264 | zinc finger protein 264 |
| ZNF446 | zinc finger protein 446 |
| ZNF552 | zinc finger protein 552 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |