deferoxamine-573 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the deferoxamine-573 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ALDOC aldolase C, fructose-bisphosphate
AMPD3 adenosine monophosphate deaminase 3
APAF1 apoptotic peptidase activating factor 1
ASCL1 achaete-scute family bHLH transcription factor 1
ASPH aspartate beta-hydroxylase
BHLHE40 basic helix-loop-helix family, member e40
BMP10 bone morphogenetic protein 10
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG2 BTG family, member 2
C19ORF66 chromosome 19 open reading frame 66
C8B complement component 8, beta polypeptide
CA6 carbonic anhydrase VI
CA9 carbonic anhydrase IX
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCNG2 cyclin G2
CD53 CD53 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRABP1 cellular retinoic acid binding protein 1
CSRP2 cysteine and glycine-rich protein 2
CTTN cortactin
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT4 DNA-damage-inducible transcript 4
DIAPH2 diaphanous-related formin 2
DISC1 disrupted in schizophrenia 1
DPYSL4 dihydropyrimidinase-like 4
EFNB3 ephrin-B3
EFR3B EFR3 homolog B (S. cerevisiae)
EGFR epidermal growth factor receptor
ENO2 enolase 2 (gamma, neuronal)
ERC1 ELKS/RAB6-interacting/CAST family member 1
FAM162A family with sequence similarity 162, member A
FAS Fas cell surface death receptor
FEM1B fem-1 homolog b (C. elegans)
FKBP8 FK506 binding protein 8, 38kDa
FOSL1 FOS-like antigen 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GBE1 glucan (1,4-alpha-), branching enzyme 1
GLDC glycine dehydrogenase (decarboxylating)
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
HILPDA hypoxia inducible lipid droplet-associated
HMOX2 heme oxygenase 2
IGFBP3 insulin-like growth factor binding protein 3
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL1B interleukin 1, beta
KDM3A lysine (K)-specific demethylase 3A
KMT2A lysine (K)-specific methyltransferase 2A
LGALS8 lectin, galactoside-binding, soluble, 8
MAPK3 mitogen-activated protein kinase 3
MED28 mediator complex subunit 28
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OBSL1 obscurin-like 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAM peptidylglycine alpha-amidating monooxygenase
PARVA parvin, alpha
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PEX11A peroxisomal biogenesis factor 11 alpha
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PICK1 protein interacting with PRKCA 1
PLK3 polo-like kinase 3
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRKCA protein kinase C, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
RHO rhodopsin
SC5D sterol-C5-desaturase
SCARB1 scavenger receptor class B, member 1
SCNN1B sodium channel, non voltage gated 1 beta subunit
SFXN3 sideroflexin 3
SH3BP2 SH3-domain binding protein 2
SIRPA signal-regulatory protein alpha
SIRT5 sirtuin 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SNTG1 syntrophin, gamma 1
SOX9 SRY (sex determining region Y)-box 9
SPAG4 sperm associated antigen 4
SPN sialophorin
STC1 stanniocalcin 1
TCP11L1 t-complex 11, testis-specific-like 1
TH tyrosine hydroxylase
TLN1 talin 1
TMEM45A transmembrane protein 45A
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TRD T cell receptor delta locus
TTR transthyretin
ULBP2 UL16 binding protein 2
VARS valyl-tRNA synthetase
WDR19 WD repeat domain 19
ZNF292 zinc finger protein 292
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ADRA2C adrenoceptor alpha 2C
ANAPC2 anaphase promoting complex subunit 2
ARRB2 arrestin, beta 2
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
B3GAT3 beta-1,3-glucuronyltransferase 3
BRD9 bromodomain containing 9
C14ORF79 chromosome 14 open reading frame 79
C1ORF109 chromosome 1 open reading frame 109
C5ORF28 chromosome 5 open reading frame 28
C7ORF43 chromosome 7 open reading frame 43
C9ORF3 chromosome 9 open reading frame 3
CBX4 chromobox homolog 4
CCDC7 coiled-coil domain containing 7
CCDC85C coiled-coil domain containing 85C
CCNB1 cyclin B1
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDR2L cerebellar degeneration-related protein 2-like
CENPB centromere protein B, 80kDa
CENPE centromere protein E, 312kDa
CEP55 centrosomal protein 55kDa
CFD complement factor D (adipsin)
CHRM4 cholinergic receptor, muscarinic 4
COBL cordon-bleu WH2 repeat protein
COL4A5 collagen, type IV, alpha 5
DHDDS dehydrodolichyl diphosphate synthase
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLK2 delta-like 2 homolog (Drosophila)
DOK5 docking protein 5
EPN3 epsin 3
ERCC4 excision repair cross-complementation group 4
ERF Ets2 repressor factor
ERMP1 endoplasmic reticulum metallopeptidase 1
EXOC2 exocyst complex component 2
FANCF Fanconi anemia, complementation group F
FASTKD5 FAST kinase domains 5
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAB2 GRB2-associated binding protein 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GCLM glutamate-cysteine ligase, modifier subunit
GEMIN6 gem (nuclear organelle) associated protein 6
GLI3 GLI family zinc finger 3
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPATCH1 G patch domain containing 1
GRWD1 glutamate-rich WD repeat containing 1
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HIST1H2BG histone cluster 1, H2bg
HIST1H2BH histone cluster 1, H2bh
HMMR hyaluronan-mediated motility receptor (RHAMM)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KPNA4 karyopherin alpha 4 (importin alpha 3)
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MED31 mediator complex subunit 31
MEFV Mediterranean fever
MNAT1 MNAT CDK-activating kinase assembly factor 1
MT4 metallothionein 4
NARFL nuclear prelamin A recognition factor-like
NPY1R neuropeptide Y receptor Y1
PDZK1IP1 PDZK1 interacting protein 1
PLEK2 pleckstrin 2
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLK1 polo-like kinase 1
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKCD protein kinase C, delta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSRC1 proline/serine-rich coiled-coil 1
PTTG3P pituitary tumor-transforming 3, pseudogene
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RASL10A RAS-like, family 10, member A
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPDL1 spindle apparatus coiled-coil protein 1
SUSD4 sushi domain containing 4
TACC3 transforming, acidic coiled-coil containing protein 3
TCEA2 transcription elongation factor A (SII), 2
TCTN1 tectonic family member 1
TKFC triokinase/FMN cyclase
TNS3 tensin 3
TRAF2 TNF receptor-associated factor 2
TSSC4 tumor suppressing subtransferable candidate 4
UBE2S ubiquitin-conjugating enzyme E2S
UNC93B1 unc-93 homolog B1 (C. elegans)
WDR13 WD repeat domain 13
ZFP36 ZFP36 ring finger protein
ZIC1 Zic family member 1
ZNF710 zinc finger protein 710