deguelin Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description An isoflavanone that has formula C23H22O6. (Chemical Entities of Biological Interest Ontology, CHEBI_4357)
External Link http://ctdbase.org/detail.go?type=chem&acc=C107676
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Genes

52 genes/proteins interacting with the chemical deguelin from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BDNF brain-derived neurotrophic factor
BIRC5 baculoviral IAP repeat containing 5
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
EGFR epidermal growth factor receptor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPAS1 endothelial PAS domain protein 1
GSK3B glycogen synthase kinase 3 beta
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL6 interleukin 6
KDR kinase insert domain receptor
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MCL1 myeloid cell leukemia 1
MKI67 marker of proliferation Ki-67
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA3 nuclear receptor coactivator 3
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS3 nitric oxide synthase 3 (endothelial cell)
NUP98 nucleoporin 98kDa
ODC1 ornithine decarboxylase 1
PARP1 poly (ADP-ribose) polymerase 1
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLCG1 phospholipase C, gamma 1
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STS steroid sulfatase (microsomal), isozyme S
TNF tumor necrosis factor
VEGFA vascular endothelial growth factor A
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase