Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the dehydrocholic acid-1523 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
ACVR1B | activin A receptor, type IB |
AGMAT | agmatine ureohydrolase (agmatinase) |
AHNAK2 | AHNAK nucleoprotein 2 |
AKAP8L | A kinase (PRKA) anchor protein 8-like |
AMPD3 | adenosine monophosphate deaminase 3 |
ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
ARL4C | ADP-ribosylation factor-like 4C |
ARR3 | arrestin 3, retinal (X-arrestin) |
ATRNL1 | attractin-like 1 |
BAIAP2 | BAI1-associated protein 2 |
BBS9 | Bardet-Biedl syndrome 9 |
C7ORF69 | chromosome 7 open reading frame 69 |
CD70 | CD70 molecule |
CDRT1 | CMT1A duplicated region transcript 1 |
CERS4 | ceramide synthase 4 |
CFHR2 | complement factor H-related 2 |
COL1A1 | collagen, type I, alpha 1 |
CORT | cortistatin |
CST1 | cystatin SN |
DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
DEFB126 | defensin, beta 126 |
DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
DNAAF1 | dynein, axonemal, assembly factor 1 |
DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
DND1 | DND microRNA-mediated repression inhibitor 1 |
DOCK5 | dedicator of cytokinesis 5 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
EPS8L3 | EPS8-like 3 |
EPYC | epiphycan |
EVA1B | eva-1 homolog B (C. elegans) |
EXOSC1 | exosome component 1 |
GEM | GTP binding protein overexpressed in skeletal muscle |
GLDC | glycine dehydrogenase (decarboxylating) |
GPC3 | glypican 3 |
GPR143 | G protein-coupled receptor 143 |
GRIP2 | glutamate receptor interacting protein 2 |
HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
HOXD1 | homeobox D1 |
HR | hair growth associated |
IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
ISG20 | interferon stimulated exonuclease gene 20kDa |
ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
KCNIP1 | Kv channel interacting protein 1 |
KHSRP | KH-type splicing regulatory protein |
KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
KRT17 | keratin 17, type I |
LMO4 | LIM domain only 4 |
LPXN | leupaxin |
LRP12 | low density lipoprotein receptor-related protein 12 |
MARK4 | MAP/microtubule affinity-regulating kinase 4 |
MET | MET proto-oncogene, receptor tyrosine kinase |
MLANA | melan-A |
MYB | v-myb avian myeloblastosis viral oncogene homolog |
MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
NF1 | neurofibromin 1 |
NNAT | neuronatin |
NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
OPTN | optineurin |
PALM | paralemmin |
PGBD5 | piggyBac transposable element derived 5 |
PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
PLAUR | plasminogen activator, urokinase receptor |
PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
PRF1 | perforin 1 (pore forming protein) |
PRODH | proline dehydrogenase (oxidase) 1 |
RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
RAP2B | RAP2B, member of RAS oncogene family |
RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
RNF122 | ring finger protein 122 |
RPL10L | ribosomal protein L10-like |
SAFB | scaffold attachment factor B |
SAMD4A | sterile alpha motif domain containing 4A |
SH3D21 | SH3 domain containing 21 |
SIRT3 | sirtuin 3 |
SLN | sarcolipin |
SND1-IT1 | SND1 intronic transcript 1 |
SOGA1 | suppressor of glucose, autophagy associated 1 |
SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
STK24 | serine/threonine kinase 24 |
SYT5 | synaptotagmin V |
SZT2 | seizure threshold 2 homolog (mouse) |
TIMELESS | timeless circadian clock |
TLN2 | talin 2 |
TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
TRIO | trio Rho guanine nucleotide exchange factor |
TUBA3C | tubulin, alpha 3c |
UCN | urocortin |
VAC14 | Vac14 homolog (S. cerevisiae) |
ZFHX4 | zinc finger homeobox 4 |
ZNF606 | zinc finger protein 606 |
Symbol | Name |
---|---|
ABHD17B | abhydrolase domain containing 17B |
ADAM15 | ADAM metallopeptidase domain 15 |
ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
ALPK1 | alpha-kinase 1 |
ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
AUH | AU RNA binding protein/enoyl-CoA hydratase |
B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
BCORL1 | BCL6 corepressor-like 1 |
BEX4 | brain expressed, X-linked 4 |
C3 | complement component 3 |
C5AR2 | complement component 5a receptor 2 |
CCDC170 | coiled-coil domain containing 170 |
CENPQ | centromere protein Q |
CNN2 | calponin 2 |
CNR2 | cannabinoid receptor 2 (macrophage) |
CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
CTSF | cathepsin F |
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
ELOVL4 | ELOVL fatty acid elongase 4 |
ELP3 | elongator acetyltransferase complex subunit 3 |
ETAA1 | Ewing tumor-associated antigen 1 |
F2R | coagulation factor II (thrombin) receptor |
FGD1 | FYVE, RhoGEF and PH domain containing 1 |
FOSL1 | FOS-like antigen 1 |
FURIN | furin (paired basic amino acid cleaving enzyme) |
GAMT | guanidinoacetate N-methyltransferase |
GDAP1 | ganglioside induced differentiation associated protein 1 |
GINS4 | GINS complex subunit 4 (Sld5 homolog) |
GRB7 | growth factor receptor-bound protein 7 |
HIST1H2AM | histone cluster 1, H2am |
IL17RA | interleukin 17 receptor A |
IL4R | interleukin 4 receptor |
IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
IPO13 | importin 13 |
IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
KLHL25 | kelch-like family member 25 |
LIN7A | lin-7 homolog A (C. elegans) |
LOC257152 | uncharacterized LOC257152 |
LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
LRP2 | low density lipoprotein receptor-related protein 2 |
MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
MBTD1 | mbt domain containing 1 |
METTL16 | methyltransferase like 16 |
MNX1 | motor neuron and pancreas homeobox 1 |
MOCS3 | molybdenum cofactor synthesis 3 |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
OSMR | oncostatin M receptor |
PADI2 | peptidyl arginine deiminase, type II |
PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
RAB30 | RAB30, member RAS oncogene family |
RAD54L2 | RAD54-like 2 (S. cerevisiae) |
RANBP17 | RAN binding protein 17 |
RARS | arginyl-tRNA synthetase |
RFTN1 | raftlin, lipid raft linker 1 |
RNF43 | ring finger protein 43 |
RPAP1 | RNA polymerase II associated protein 1 |
RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
SCD5 | stearoyl-CoA desaturase 5 |
SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
SFT2D2 | SFT2 domain containing 2 |
SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
SOAT1 | sterol O-acyltransferase 1 |
SPIDR | scaffolding protein involved in DNA repair |
SULT4A1 | sulfotransferase family 4A, member 1 |
SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
TFF2 | trefoil factor 2 |
THAP1 | THAP domain containing, apoptosis associated protein 1 |
THBS3 | thrombospondin 3 |
TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
TMEM104 | transmembrane protein 104 |
TMEM180 | transmembrane protein 180 |
TRAIP | TRAF interacting protein |
TRIM5 | tripartite motif containing 5 |
UPP1 | uridine phosphorylase 1 |
WDR25 | WD repeat domain 25 |
WDR4 | WD repeat domain 4 |
ZBTB6 | zinc finger and BTB domain containing 6 |
ZNF180 | zinc finger protein 180 |
ZNF205 | zinc finger protein 205 |
ZNF211 | zinc finger protein 211 |
ZNF394 | zinc finger protein 394 |
ZNF428 | zinc finger protein 428 |
ZNF480 | zinc finger protein 480 |
ZNF652 | zinc finger protein 652 |
ZNF665 | zinc finger protein 665 |
ZNF76 | zinc finger protein 76 |