Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the dehydrocholic acid-1940 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD5 | abhydrolase domain containing 5 |
ACRV1 | acrosomal vesicle protein 1 |
ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
ANGEL1 | angel homolog 1 (Drosophila) |
APOD | apolipoprotein D |
ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
ATG10 | autophagy related 10 |
ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
ATXN7L3B | ataxin 7-like 3B |
B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
CA7 | carbonic anhydrase VII |
CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
CLCN7 | chloride channel, voltage-sensitive 7 |
CLTCL1 | clathrin, heavy chain-like 1 |
COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
COPS7B | COP9 signalosome subunit 7B |
CRMP1 | collapsin response mediator protein 1 |
CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 |
DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 |
DENND1C | DENN/MADD domain containing 1C |
DLK2 | delta-like 2 homolog (Drosophila) |
DPF3 | D4, zinc and double PHD fingers, family 3 |
DTNA | dystrobrevin, alpha |
FBLN1 | fibulin 1 |
FMO2 | flavin containing monooxygenase 2 (non-functional) |
FZD8 | frizzled class receptor 8 |
GHRHR | growth hormone releasing hormone receptor |
GLE1 | GLE1 RNA export mediator |
GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
GPN3 | GPN-loop GTPase 3 |
GPR1 | G protein-coupled receptor 1 |
GPR27 | G protein-coupled receptor 27 |
HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
HFE | hemochromatosis |
HLA-G | major histocompatibility complex, class I, G |
HMOX2 | heme oxygenase 2 |
HNF1B | HNF1 homeobox B |
HOXD9 | homeobox D9 |
HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
IFT81 | intraflagellar transport 81 |
IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
KCTD15 | potassium channel tetramerization domain containing 15 |
KIAA0141 | KIAA0141 |
KLHL9 | kelch-like family member 9 |
LDLRAP1 | low density lipoprotein receptor adaptor protein 1 |
LMF2 | lipase maturation factor 2 |
MAEA | macrophage erythroblast attacher |
MAN1C1 | mannosidase, alpha, class 1C, member 1 |
MEF2A | myocyte enhancer factor 2A |
MFGE8 | milk fat globule-EGF factor 8 protein |
MLH3 | mutL homolog 3 |
MNS1 | meiosis-specific nuclear structural 1 |
MR1 | major histocompatibility complex, class I-related |
MSH3 | mutS homolog 3 |
MTG1 | mitochondrial ribosome-associated GTPase 1 |
NELL2 | NEL-like 2 (chicken) |
NPTXR | neuronal pentraxin receptor |
NTHL1 | nth endonuclease III-like 1 (E. coli) |
NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
OSBPL2 | oxysterol binding protein-like 2 |
PARM1 | prostate androgen-regulated mucin-like protein 1 |
PARVA | parvin, alpha |
PDGFD | platelet derived growth factor D |
PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
PLLP | plasmolipin |
POFUT1 | protein O-fucosyltransferase 1 |
POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
PTAFR | platelet-activating factor receptor |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
RIOK3 | RIO kinase 3 |
RNF39 | ring finger protein 39 |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
S1PR1 | sphingosine-1-phosphate receptor 1 |
SASH3 | SAM and SH3 domain containing 3 |
SFTPB | surfactant protein B |
SIRT3 | sirtuin 3 |
SKAP1 | src kinase associated phosphoprotein 1 |
SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
SLIT1 | slit homolog 1 (Drosophila) |
SMG7 | SMG7 nonsense mediated mRNA decay factor |
SNX11 | sorting nexin 11 |
STARD3 | StAR-related lipid transfer (START) domain containing 3 |
TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
TBXA2R | thromboxane A2 receptor |
TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
TDP1 | tyrosyl-DNA phosphodiesterase 1 |
TMEM132A | transmembrane protein 132A |
TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
VIPR2 | vasoactive intestinal peptide receptor 2 |
VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
ZHX3 | zinc fingers and homeoboxes 3 |
ZNF609 | zinc finger protein 609 |
Symbol | Name |
---|---|
ABHD3 | abhydrolase domain containing 3 |
ACAD8 | acyl-CoA dehydrogenase family, member 8 |
ACD | adrenocortical dysplasia homolog (mouse) |
ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
ACVR2A | activin A receptor, type IIA |
AMOTL2 | angiomotin like 2 |
AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
APH1A | APH1A gamma secretase subunit |
B3GNT1 | |
BARD1 | BRCA1 associated RING domain 1 |
C9ORF3 | chromosome 9 open reading frame 3 |
CDC45 | cell division cycle 45 |
CEP85 | centrosomal protein 85kDa |
CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
CISH | cytokine inducible SH2-containing protein |
CKB | creatine kinase, brain |
CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
CPOX | coproporphyrinogen oxidase |
DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
DKFZP586I1420 | uncharacterized protein DKFZp586I1420 |
DMTN | dematin actin binding protein |
DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
ERMP1 | endoplasmic reticulum metallopeptidase 1 |
EVPL | envoplakin |
FADS2 | fatty acid desaturase 2 |
FBXW12 | F-box and WD repeat domain containing 12 |
GAMT | guanidinoacetate N-methyltransferase |
GCC1 | GRIP and coiled-coil domain containing 1 |
GID4 | GID complex subunit 4 |
H1F0 | H1 histone family, member 0 |
HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
HEATR3 | HEAT repeat containing 3 |
HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
HSPA4L | heat shock 70kDa protein 4-like |
IMPAD1 | inositol monophosphatase domain containing 1 |
IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
JOSD1 | Josephin domain containing 1 |
KIF23 | kinesin family member 23 |
KRT34 | keratin 34, type I |
LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
LYPD1 | LY6/PLAUR domain containing 1 |
MAP1S | microtubule-associated protein 1S |
MED17 | mediator complex subunit 17 |
MUTYH | mutY homolog |
NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
NDE1 | nudE neurodevelopment protein 1 |
NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 |
NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
NOD1 | nucleotide-binding oligomerization domain containing 1 |
NT5E | 5'-nucleotidase, ecto (CD73) |
NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
OARD1 | O-acyl-ADP-ribose deacylase 1 |
PADI1 | peptidyl arginine deiminase, type I |
PCNP | PEST proteolytic signal containing nuclear protein |
PMM2 | phosphomannomutase 2 |
POTEKP | POTE ankyrin domain family, member K, pseudogene |
PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
PRR11 | proline rich 11 |
PSENEN | presenilin enhancer gamma secretase subunit |
PTX3 | pentraxin 3, long |
QDPR | quinoid dihydropteridine reductase |
RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 |
RBBP5 | retinoblastoma binding protein 5 |
REPIN1 | replication initiator 1 |
RIC8A | RIC8 guanine nucleotide exchange factor A |
SARS2 | seryl-tRNA synthetase 2, mitochondrial |
SCML1 | sex comb on midleg-like 1 (Drosophila) |
SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
SOAT1 | sterol O-acyltransferase 1 |
SP140L | SP140 nuclear body protein-like |
STARD13 | StAR-related lipid transfer (START) domain containing 13 |
STK25 | serine/threonine kinase 25 |
STRN4 | striatin, calmodulin binding protein 4 |
TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
TERF2 | telomeric repeat binding factor 2 |
TEX30 | testis expressed 30 |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
THG1L | tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) |
TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
TMEM115 | transmembrane protein 115 |
TMEM164 | transmembrane protein 164 |
TMEM260 | transmembrane protein 260 |
TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A |
TOE1 | target of EGR1, member 1 (nuclear) |
TOLLIP | toll interacting protein |
TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
TRAPPC12 | trafficking protein particle complex 12 |
TRHDE | thyrotropin-releasing hormone degrading enzyme |
UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
WLS | wntless Wnt ligand secretion mediator |
ZFHX4 | zinc finger homeobox 4 |
ZFP36 | ZFP36 ring finger protein |
ZHX2 | zinc fingers and homeoboxes 2 |
ZNF394 | zinc finger protein 394 |
ZNF532 | zinc finger protein 532 |
ZNF623 | zinc finger protein 623 |