Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the dehydrocholic acid-2023 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACAN | aggrecan |
ADK | adenosine kinase |
AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
BCL7A | B-cell CLL/lymphoma 7A |
C1ORF109 | chromosome 1 open reading frame 109 |
C1ORF61 | chromosome 1 open reading frame 61 |
C22ORF24 | chromosome 22 open reading frame 24 |
CACFD1 | calcium channel flower domain containing 1 |
CAST | calpastatin |
CCPG1 | cell cycle progression 1 |
CD101 | CD101 molecule |
CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 |
CD5 | CD5 molecule |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CEP152 | centrosomal protein 152kDa |
CETN1 | centrin, EF-hand protein, 1 |
CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
CLIC5 | chloride intracellular channel 5 |
COG5 | component of oligomeric golgi complex 5 |
CREB3 | cAMP responsive element binding protein 3 |
CTSS | cathepsin S |
CUL3 | cullin 3 |
DDR1 | discoidin domain receptor tyrosine kinase 1 |
DERL1 | derlin 1 |
DIAPH1 | diaphanous-related formin 1 |
DIEXF | digestive organ expansion factor homolog (zebrafish) |
DND1 | DND microRNA-mediated repression inhibitor 1 |
DSN1 | DSN1, MIS12 kinetochore complex component |
DST | dystonin |
EIF4E | eukaryotic translation initiation factor 4E |
EIF4E2 | eukaryotic translation initiation factor 4E family member 2 |
ELMO2 | engulfment and cell motility 2 |
EPHB4 | EPH receptor B4 |
FADS2 | fatty acid desaturase 2 |
FCHO1 | FCH domain only 1 |
FOSL1 | FOS-like antigen 1 |
FYB | FYN binding protein |
GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
GPX2 | glutathione peroxidase 2 |
HIRA | histone cell cycle regulator |
HIST1H3E | histone cluster 1, H3e |
HNF1A | HNF1 homeobox A |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
ITSN1 | intersectin 1 (SH3 domain protein) |
KIFC1 | kinesin family member C1 |
KLHL20 | kelch-like family member 20 |
LPP | LIM domain containing preferred translocation partner in lipoma |
LRRN2 | leucine rich repeat neuronal 2 |
MAPK13 | mitogen-activated protein kinase 13 |
MFSD11 | major facilitator superfamily domain containing 11 |
MSH3 | mutS homolog 3 |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NUP160 | nucleoporin 160kDa |
PAPPA2 | pappalysin 2 |
PARG | poly (ADP-ribose) glycohydrolase |
PBX2 | pre-B-cell leukemia homeobox 2 |
PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
PLCB2 | phospholipase C, beta 2 |
PLS1 | plastin 1 |
PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
PRPH2 | peripherin 2 (retinal degeneration, slow) |
PSG6 | pregnancy specific beta-1-glycoprotein 6 |
RAD21 | RAD21 homolog (S. pombe) |
RAD23B | RAD23 homolog B (S. cerevisiae) |
RBBP5 | retinoblastoma binding protein 5 |
RCAN1 | regulator of calcineurin 1 |
RNF208 | ring finger protein 208 |
RP2 | retinitis pigmentosa 2 (X-linked recessive) |
RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
SERINC5 | serine incorporator 5 |
SIRT5 | sirtuin 5 |
SLC22A18 | solute carrier family 22, member 18 |
SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
SPIDR | scaffolding protein involved in DNA repair |
SPN | sialophorin |
SPTSSA | serine palmitoyltransferase, small subunit A |
SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
SRSF11 | serine/arginine-rich splicing factor 11 |
STIM1 | stromal interaction molecule 1 |
STMN1 | stathmin 1 |
SUGP1 | SURP and G patch domain containing 1 |
TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
TCP11L1 | t-complex 11, testis-specific-like 1 |
TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
TPSG1 | tryptase gamma 1 |
TXN2 | thioredoxin 2 |
UEVLD | UEV and lactate/malate dehyrogenase domains |
WDR19 | WD repeat domain 19 |
YIPF2 | Yip1 domain family, member 2 |
ZC4H2 | zinc finger, C4H2 domain containing |
ZNF280D | zinc finger protein 280D |
ZNF79 | zinc finger protein 79 |
Symbol | Name |
---|---|
ACP6 | acid phosphatase 6, lysophosphatidic |
ADM2 | adrenomedullin 2 |
AEN | apoptosis enhancing nuclease |
ALPK1 | alpha-kinase 1 |
ANXA6 | annexin A6 |
AQP2 | aquaporin 2 (collecting duct) |
ARG1 | arginase 1 |
ASAP1-IT1 | ASAP1 intronic transcript 1 |
ASCC2 | activating signal cointegrator 1 complex subunit 2 |
ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
BCKDK | branched chain ketoacid dehydrogenase kinase |
BCL7C | B-cell CLL/lymphoma 7C |
CBR1 | carbonyl reductase 1 |
CCNL2 | cyclin L2 |
CDCA3 | cell division cycle associated 3 |
CEP72 | centrosomal protein 72kDa |
CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
CLK3 | CDC-like kinase 3 |
CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
CPTP | ceramide-1-phosphate transfer protein |
CTAGE9 | CTAGE family, member 9 |
CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
DDB2 | damage-specific DNA binding protein 2, 48kDa |
EDAR | ectodysplasin A receptor |
EDC3 | enhancer of mRNA decapping 3 |
ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
FAM193B | family with sequence similarity 193, member B |
FBXL15 | F-box and leucine-rich repeat protein 15 |
FKBP2 | FK506 binding protein 2, 13kDa |
GAB2 | GRB2-associated binding protein 2 |
GALT | galactose-1-phosphate uridylyltransferase |
GMPPA | GDP-mannose pyrophosphorylase A |
GPALPP1 | GPALPP motifs containing 1 |
GSTM5 | glutathione S-transferase mu 5 |
H2BFS | H2B histone family, member S (pseudogene) |
HAGH | hydroxyacylglutathione hydrolase |
IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
IL4R | interleukin 4 receptor |
ILK | integrin-linked kinase |
INA | internexin neuronal intermediate filament protein, alpha |
IP6K1 | inositol hexakisphosphate kinase 1 |
KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
KIFAP3 | kinesin-associated protein 3 |
KRI1 | KRI1 homolog (S. cerevisiae) |
LGALS9 | lectin, galactoside-binding, soluble, 9 |
LRRC42 | leucine rich repeat containing 42 |
LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
LZTR1 | leucine-zipper-like transcription regulator 1 |
MAGOHB | mago-nashi homolog B (Drosophila) |
MICALL2 | MICAL-like 2 |
MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
MXRA8 | matrix-remodelling associated 8 |
NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma |
NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
NCKAP1L | NCK-associated protein 1-like |
NPPA | natriuretic peptide A |
NSD1 | nuclear receptor binding SET domain protein 1 |
NUBP2 | nucleotide binding protein 2 |
NUP93 | nucleoporin 93kDa |
NVL | nuclear VCP-like |
OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
PALM | paralemmin |
PAN2 | PAN2 poly(A) specific ribonuclease subunit |
PCSK7 | proprotein convertase subtilisin/kexin type 7 |
PEX12 | peroxisomal biogenesis factor 12 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
PMEL | premelanosome protein |
PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
RAB5C | RAB5C, member RAS oncogene family |
RABEPK | Rab9 effector protein with kelch motifs |
RAD9A | RAD9 homolog A (S. pombe) |
RBM47 | RNA binding motif protein 47 |
RBMS3 | RNA binding motif, single stranded interacting protein 3 |
RHBDD3 | rhomboid domain containing 3 |
SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
SMAD7 | SMAD family member 7 |
TEX40 | testis expressed 40 |
TIAM2 | T-cell lymphoma invasion and metastasis 2 |
TMEM14A | transmembrane protein 14A |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TMEM214 | transmembrane protein 214 |
TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
TUBA4B | tubulin, alpha 4b |
UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
UCKL1 | uridine-cytidine kinase 1-like 1 |
UNKL | unkempt family zinc finger-like |
USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
YY2 | YY2 transcription factor |
ZCCHC8 | zinc finger, CCHC domain containing 8 |
ZNF33B | zinc finger protein 33B |
ZNF408 | zinc finger protein 408 |