dehydrocholic acid-5681 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the dehydrocholic acid-5681 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAM8 ADAM metallopeptidase domain 8
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AGTR1 angiotensin II receptor, type 1
AHSP alpha hemoglobin stabilizing protein
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANGPTL2 angiopoietin-like 2
ARSD arylsulfatase D
ASTN1 astrotactin 1
ATXN2L ataxin 2-like
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BUD31 BUD31 homolog (S. cerevisiae)
CCKAR cholecystokinin A receptor
CD6 CD6 molecule
CDH16 cadherin 16, KSP-cadherin
CEP295 centrosomal protein 295kDa
CHI3L2 chitinase 3-like 2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CNTNAP2 contactin associated protein-like 2
COL5A2 collagen, type V, alpha 2
CSHL1 chorionic somatomammotropin hormone-like 1
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CXCR6 chemokine (C-X-C motif) receptor 6
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DGCR6L DiGeorge syndrome critical region gene 6-like
DLX4 distal-less homeobox 4
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DTX2 deltex 2, E3 ubiquitin ligase
E2F4 E2F transcription factor 4, p107/p130-binding
ERCC2 excision repair cross-complementation group 2
ETV5 ets variant 5
FGF6 fibroblast growth factor 6
GPR137 G protein-coupled receptor 137
GPR157 G protein-coupled receptor 157
GRM4 glutamate receptor, metabotropic 4
GYPB glycophorin B (MNS blood group)
HIC2 hypermethylated in cancer 2
HIST1H2BN histone cluster 1, H2bn
IGHM immunoglobulin heavy constant mu
IGLV1-44 immunoglobulin lambda variable 1-44
IL17RA interleukin 17 receptor A
IL1B interleukin 1, beta
ING2 inhibitor of growth family, member 2
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LOXL3 lysyl oxidase-like 3
LRRN2 leucine rich repeat neuronal 2
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MYT1 myelin transcription factor 1
NFX1 nuclear transcription factor, X-box binding 1
NOL10 nucleolar protein 10
NPAP1 nuclear pore associated protein 1
NRN1 neuritin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NYNRIN NYN domain and retroviral integrase containing
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PARP11 poly (ADP-ribose) polymerase family, member 11
PGLYRP4 peptidoglycan recognition protein 4
PITX1 paired-like homeodomain 1
PRMT8 protein arginine methyltransferase 8
PSD3 pleckstrin and Sec7 domain containing 3
PTPRD protein tyrosine phosphatase, receptor type, D
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RGS5 regulator of G-protein signaling 5
RUNX1 runt-related transcription factor 1
SCRT1 scratch family zinc finger 1
SETBP1 SET binding protein 1
SFRP4 secreted frizzled-related protein 4
SGK2 serum/glucocorticoid regulated kinase 2
SHOX2 short stature homeobox 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SIX3 SIX homeobox 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF7 serine/arginine-rich splicing factor 7
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBCD tubulin folding cofactor D
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTC12 tetratricopeptide repeat domain 12
UBXN1 UBX domain protein 1
UPK3B uroplakin 3B
VCX2 variable charge, X-linked 2
ZFP2 ZFP2 zinc finger protein
ZNF484 zinc finger protein 484
ZNF646 zinc finger protein 646
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AFF4 AF4/FMR2 family, member 4
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C11ORF80 chromosome 11 open reading frame 80
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C21ORF91 chromosome 21 open reading frame 91
C22ORF29 chromosome 22 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDADC1 cytidine and dCMP deaminase domain containing 1
CENPQ centromere protein Q
CFAP44 cilia and flagella associated protein 44
CHKB choline kinase beta
CHMP6 charged multivesicular body protein 6
CIC capicua transcriptional repressor
CNGB3 cyclic nucleotide gated channel beta 3
CXORF56 chromosome X open reading frame 56
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DTX4 deltex 4, E3 ubiquitin ligase
EFCAB2 EF-hand calcium binding domain 2
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
FAN1 FANCD2/FANCI-associated nuclease 1
FANCE Fanconi anemia, complementation group E
FKBP5 FK506 binding protein 5
FSD1 fibronectin type III and SPRY domain containing 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GLI3 GLI family zinc finger 3
GPALPP1 GPALPP motifs containing 1
GPR27 G protein-coupled receptor 27
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPX2 glutathione peroxidase 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
INCENP inner centromere protein antigens 135/155kDa
KCNK15 potassium channel, two pore domain subfamily K, member 15
KLF11 Kruppel-like factor 11
KLF3 Kruppel-like factor 3 (basic)
LARP6 La ribonucleoprotein domain family, member 6
LOC100286895 cell division cycle 27 homolog pseudogene
LONP2 lon peptidase 2, peroxisomal
LZTFL1 leucine zipper transcription factor-like 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
NEK11 NIMA-related kinase 11
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5DC3 5'-nucleotidase domain containing 3
NUP62CL nucleoporin 62kDa C-terminal like
NXPE3 neurexophilin and PC-esterase domain family, member 3
OCA2 oculocutaneous albinism II
OTUD3 OTU deubiquitinase 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PGBD5 piggyBac transposable element derived 5
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLD3 phospholipase D family, member 3
PODNL1 podocan-like 1
RAB3D RAB3D, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RCAN3 RCAN family member 3
RPH3AL rabphilin 3A-like (without C2 domains)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SHARPIN SHANK-associated RH domain interactor
SND1-IT1 SND1 intronic transcript 1
SPAG4 sperm associated antigen 4
SPRYD7 SPRY domain containing 7
STARD5 StAR-related lipid transfer (START) domain containing 5
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBR1 T-box, brain, 1
TGFBR3 transforming growth factor, beta receptor III
THAP1 THAP domain containing, apoptosis associated protein 1
TMEM180 transmembrane protein 180
TMEM19 transmembrane protein 19
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TREM1 triggering receptor expressed on myeloid cells 1
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
VIM vimentin
WDR33 WD repeat domain 33
XK X-linked Kx blood group
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF134 zinc finger protein 134
ZNF205 zinc finger protein 205
ZNF211 zinc finger protein 211
ZNF286A zinc finger protein 286A
ZNF606 zinc finger protein 606
ZSCAN26 zinc finger and SCAN domain containing 26