delayed neural tube closure Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description delay in the last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline (Mammalian Phenotype Ontology, MP_0002621)
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25 gene mutations causing the delayed neural tube closure phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APAF1 apoptotic peptidase activating factor 1
CECR2 cat eye syndrome chromosome region, candidate 2
CSK c-src tyrosine kinase
EPCAM epithelial cell adhesion molecule
FOLR1 folate receptor 1 (adult)
GLI3 GLI family zinc finger 3
GLMN glomulin, FKBP associated protein
GRHL3 grainyhead-like 3 (Drosophila)
HOXA1 homeobox A1
JARID2 jumonji, AT rich interactive domain 2
LRP2 low density lipoprotein receptor-related protein 2
MDFI MyoD family inhibitor
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
PAX2 paired box 2
PAX3 paired box 3
RAX retina and anterior neural fold homeobox
RYBP RING1 and YY1 binding protein
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC31A1 solute carrier family 31 (copper transporter), member 1
SMAD5 SMAD family member 5
STIL SCL/TAL1 interrupting locus
TCOF1 Treacher Collins-Franceschetti syndrome 1
VANGL2 VANGL planar cell polarity protein 2
ZIC2 Zic family member 2
ZIC3 Zic family member 3