delsoline-6075 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the delsoline-6075 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AJAP1 adherens junctions associated protein 1
ALDOB aldolase B, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMPD1 adenosine monophosphate deaminase 1
APAF1 apoptotic peptidase activating factor 1
APOL3 apolipoprotein L, 3
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARTN artemin
ASB1 ankyrin repeat and SOCS box containing 1
ATXN2L ataxin 2-like
BTK Bruton agammaglobulinemia tyrosine kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CD200 CD200 molecule
CD300C CD300c molecule
CD58 CD58 molecule
CEP41 centrosomal protein 41kDa
COL16A1 collagen, type XVI, alpha 1
COL3A1 collagen, type III, alpha 1
COL7A1 collagen, type VII, alpha 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DES desmin
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPY19L1 dpy-19-like 1 (C. elegans)
EDA ectodysplasin A
EGF epidermal growth factor
EGFL6 EGF-like-domain, multiple 6
EXOSC2 exosome component 2
FGF4 fibroblast growth factor 4
FGFBP1 fibroblast growth factor binding protein 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GBP2 guanylate binding protein 2, interferon-inducible
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GLB1L galactosidase, beta 1-like
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR3 G protein-coupled receptor 3
GYG2 glycogenin 2
GZMK granzyme K (granzyme 3; tryptase II)
HFE hemochromatosis
HPX hemopexin
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IL11 interleukin 11
IL1RN interleukin 1 receptor antagonist
IL36RN interleukin 36 receptor antagonist
INA internexin neuronal intermediate filament protein, alpha
IPW imprinted in Prader-Willi syndrome (non-protein coding)
JAK3 Janus kinase 3
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIF25 kinesin family member 25
KLK8 kallikrein-related peptidase 8
KRTAP2-4 keratin associated protein 2-4
LAMC3 laminin, gamma 3
LARP4B La ribonucleoprotein domain family, member 4B
LEFTY2 left-right determination factor 2
LOC157562 uncharacterized LOC157562
LRRC23 leucine rich repeat containing 23
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK8 mitogen-activated protein kinase 8
MBD2 methyl-CpG binding domain protein 2
MCTP2 multiple C2 domains, transmembrane 2
MEF2D myocyte enhancer factor 2D
MTCP1 mature T-cell proliferation 1
MTMR8 myotubularin related protein 8
MYF5 myogenic factor 5
N4BP2L1 NEDD4 binding protein 2-like 1
NPAS2 neuronal PAS domain protein 2
NPHP1 nephronophthisis 1 (juvenile)
PAOX polyamine oxidase (exo-N4-amino)
PDE4C phosphodiesterase 4C, cAMP-specific
PF4 platelet factor 4
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
POU3F1 POU class 3 homeobox 1
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PSG4 pregnancy specific beta-1-glycoprotein 4
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RELN reelin
RGS12 regulator of G-protein signaling 12
RGS20 regulator of G-protein signaling 20
RNF126P1 ring finger protein 126 pseudogene 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SIRT5 sirtuin 5
SLC19A1 solute carrier family 19 (folate transporter), member 1
SMAD1 SMAD family member 1
SNTG1 syntrophin, gamma 1
SPN sialophorin
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STAT2 signal transducer and activator of transcription 2, 113kDa
TBC1D29 TBC1 domain family, member 29
TEK TEK tyrosine kinase, endothelial
TENM4 teneurin transmembrane protein 4
TLDC1 TBC/LysM-associated domain containing 1
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIL TLR4 interactor with leucine-rich repeats
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACAD10 acyl-CoA dehydrogenase family, member 10
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAG4 BCL2-associated athanogene 4
BGLAP bone gamma-carboxyglutamate (gla) protein
C4ORF29 chromosome 4 open reading frame 29
CIDEB cell death-inducing DFFA-like effector b
CISH cytokine inducible SH2-containing protein
CLDN15 claudin 15
CNGB3 cyclic nucleotide gated channel beta 3
CORO7 coronin 7
CRIP1 cysteine-rich protein 1 (intestinal)
CSF1R colony stimulating factor 1 receptor
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DIXDC1 DIX domain containing 1
DNM1 dynamin 1
DUSP9 dual specificity phosphatase 9
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
DYSF dysferlin
FBXO22 F-box protein 22
FLT4 fms-related tyrosine kinase 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GRTP1 growth hormone regulated TBC protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIRA histone cell cycle regulator
HOXB2 homeobox B2
IFT54 intraflagellar transport 54
IL4R interleukin 4 receptor
JMJD4 jumonji domain containing 4
JRKL JRK-like
KCTD7 potassium channel tetramerization domain containing 7
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KREMEN2 kringle containing transmembrane protein 2
KRT24 keratin 24, type I
LAMB3 laminin, beta 3
LOC729164 hCG1732469
LOXL3 lysyl oxidase-like 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC61 leucine rich repeat containing 61
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAST3 microtubule associated serine/threonine kinase 3
MGC12488
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NUP62CL nucleoporin 62kDa C-terminal like
OLFML2A olfactomedin-like 2A
OSGIN1 oxidative stress induced growth inhibitor 1
PAIP2B poly(A) binding protein interacting protein 2B
PER3 period circadian clock 3
PGPEP1 pyroglutamyl-peptidase I
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PORCN porcupine homolog (Drosophila)
PRF1 perforin 1 (pore forming protein)
PRODH proline dehydrogenase (oxidase) 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTK6 protein tyrosine kinase 6
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRE protein tyrosine phosphatase, receptor type, E
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCAN3 RCAN family member 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SCAI suppressor of cancer cell invasion
SCN1B sodium channel, voltage gated, type I beta subunit
SLC12A8 solute carrier family 12, member 8
SLC17A2 solute carrier family 17, member 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SRD5A3 steroid 5 alpha-reductase 3
STRN striatin, calmodulin binding protein
SYT17 synaptotagmin XVII
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D17 TBC1 domain family, member 17
TBX19 T-box 19
TMC7 transmembrane channel-like 7
TMCC2 transmembrane and coiled-coil domain family 2
TMEM120B transmembrane protein 120B
TRIM21 tripartite motif containing 21
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
VGF VGF nerve growth factor inducible
VWA9 von Willebrand factor A domain containing 9
WLS wntless Wnt ligand secretion mediator
XAB2 XPA binding protein 2
ZMYM3 zinc finger, MYM-type 3
ZNF286A zinc finger protein 286A
ZNF446 zinc finger protein 446