| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the demeclocycline-3604 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAMDEC1 | ADAM-like, decysin 1 |
| ANGPTL2 | angiopoietin-like 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CARTPT | CART prepropeptide |
| CD52 | CD52 molecule |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CIB2 | calcium and integrin binding family member 2 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| COL2A1 | collagen, type II, alpha 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DAPK2 | death-associated protein kinase 2 |
| DCTN2 | dynactin 2 (p50) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EFNB3 | ephrin-B3 |
| EGR1 | early growth response 1 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| EPHB2 | EPH receptor B2 |
| EXPH5 | exophilin 5 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FUT5 | fucosyltransferase 5 (alpha (1,3) fucosyltransferase) |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GGT1 | gamma-glutamyltransferase 1 |
| GM2A | GM2 ganglioside activator |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR15 | G protein-coupled receptor 15 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSTM5 | glutathione S-transferase mu 5 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IL11RA | interleukin 11 receptor, alpha |
| INA | internexin neuronal intermediate filament protein, alpha |
| ITIH4 | inter-alpha-trypsin inhibitor heavy chain family, member 4 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KIAA1024 | KIAA1024 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLHL28 | kelch-like family member 28 |
| KRT2 | keratin 2, type II |
| LAMA4 | laminin, alpha 4 |
| LBH | limb bud and heart development |
| LOC647070 | uncharacterized LOC647070 |
| LOX | lysyl oxidase |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MEGF6 | multiple EGF-like-domains 6 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MON2 | MON2 homolog (S. cerevisiae) |
| NDRG2 | NDRG family member 2 |
| NELL2 | NEL-like 2 (chicken) |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 |
| P3H2 | prolyl 3-hydroxylase 2 |
| PCDH1 | protocadherin 1 |
| PCDH12 | protocadherin 12 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PLIN2 | perilipin 2 |
| PLLP | plasmolipin |
| POPDC3 | popeye domain containing 3 |
| PRDM10 | PR domain containing 10 |
| PRDM16 | PR domain containing 16 |
| PRKCQ | protein kinase C, theta |
| PTAFR | platelet-activating factor receptor |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBBP9 | retinoblastoma binding protein 9 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RND1 | Rho family GTPase 1 |
| RPL18 | ribosomal protein L18 |
| RUNDC3A | RUN domain containing 3A |
| SBSPON | somatomedin B and thrombospondin, type 1 domain containing |
| SCG2 | secretogranin II |
| SECTM1 | secreted and transmembrane 1 |
| SELL | selectin L |
| SERHL2 | serine hydrolase-like 2 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPTA1 | spectrin, alpha, erythrocytic 1 |
| SYN2 | synapsin II |
| TAOK2 | TAO kinase 2 |
| TCF4 | transcription factor 4 |
| TFEB | transcription factor EB |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TP63 | tumor protein p63 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| XAF1 | XIAP associated factor 1 |
| ZNF304 | zinc finger protein 304 |
| Symbol | Name |
|---|---|
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AMT | aminomethyltransferase |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CENPO | centromere protein O |
| CLSTN2 | calsyntenin 2 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DOK2 | docking protein 2, 56kDa |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| DYSF | dysferlin |
| EFNA3 | ephrin-A3 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAAH | fatty acid amide hydrolase |
| FAM76A | family with sequence similarity 76, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GOLGA8B | golgin A8 family, member B |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2BJ | histone cluster 1, H2bj |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INO80D | INO80 complex subunit D |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KLF2 | Kruppel-like factor 2 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KRT15 | keratin 15, type I |
| LIF | leukemia inhibitory factor |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRRC61 | leucine rich repeat containing 61 |
| LYRM9 | LYR motif containing 9 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTA2 | metastasis associated 1 family, member 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NOTCH1 | notch 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OLFML2A | olfactomedin-like 2A |
| ONECUT2 | one cut homeobox 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PADI1 | peptidyl arginine deiminase, type I |
| PADI2 | peptidyl arginine deiminase, type II |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGR | progesterone receptor |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLXNA3 | plexin A3 |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| RAB3D | RAB3D, member RAS oncogene family |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| ROM1 | retinal outer segment membrane protein 1 |
| RPL10L | ribosomal protein L10-like |
| S100A4 | S100 calcium binding protein A4 |
| SDC3 | syndecan 3 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SIX1 | SIX homeobox 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLPI | secretory leukocyte peptidase inhibitor |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TDRD1 | tudor domain containing 1 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TLR2 | toll-like receptor 2 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIM21 | tripartite motif containing 21 |
| TUBA3C | tubulin, alpha 3c |
| UNKL | unkempt family zinc finger-like |
| USP19 | ubiquitin specific peptidase 19 |
| WDR25 | WD repeat domain 25 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF721 | zinc finger protein 721 |
| ZNF770 | zinc finger protein 770 |
