| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the demeclocycline-3706 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ADRA1D | adrenoceptor alpha 1D |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APOL6 | apolipoprotein L, 6 |
| ARTN | artemin |
| ASPH | aspartate beta-hydroxylase |
| BMP7 | bone morphogenetic protein 7 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CBLC | Cbl proto-oncogene C, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CCNT2 | cyclin T2 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| CDK18 | cyclin-dependent kinase 18 |
| CHM | choroideremia (Rab escort protein 1) |
| CLDN11 | claudin 11 |
| COL7A1 | collagen, type VII, alpha 1 |
| CREM | cAMP responsive element modulator |
| CT55 | cancer/testis antigen 55 |
| CT62 | cancer/testis antigen 62 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP2 | dual specificity phosphatase 2 |
| ECE1 | endothelin converting enzyme 1 |
| EGFR | epidermal growth factor receptor |
| EGR1 | early growth response 1 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| EPHB1 | EPH receptor B1 |
| FAS | Fas cell surface death receptor |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FRMD4A | FERM domain containing 4A |
| GAP43 | growth associated protein 43 |
| GGT1 | gamma-glutamyltransferase 1 |
| GRM2 | glutamate receptor, metabotropic 2 |
| HIST1H2AL | histone cluster 1, H2al |
| HPX | hemopexin |
| HRG | histidine-rich glycoprotein |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IFI44 | interferon-induced protein 44 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA17 | interferon, alpha 17 |
| IGL | immunoglobulin lambda locus |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KLK12 | kallikrein-related peptidase 12 |
| KLK13 | kallikrein-related peptidase 13 |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 |
| LDLR | low density lipoprotein receptor |
| LIMK2 | LIM domain kinase 2 |
| LPIN1 | lipin 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LRTM1 | leucine-rich repeats and transmembrane domains 1 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MCFD2 | multiple coagulation factor deficiency 2 |
| MEF2C | myocyte enhancer factor 2C |
| MEF2D | myocyte enhancer factor 2D |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MRC2 | mannose receptor, C type 2 |
| MUC3A | mucin 3A, cell surface associated |
| MYOZ1 | myozenin 1 |
| NFRKB | nuclear factor related to kappaB binding protein |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NRP1 | neuropilin 1 |
| NRP2 | neuropilin 2 |
| NTF3 | neurotrophin 3 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RASL11B | RAS-like, family 11, member B |
| RBBP9 | retinoblastoma binding protein 9 |
| RECQL5 | RecQ protein-like 5 |
| RPL18 | ribosomal protein L18 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPAG11A | sperm associated antigen 11A |
| SYNDIG1 | synapse differentiation inducing 1 |
| SYNJ1 | synaptojanin 1 |
| TAF7L | TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa |
| TBL2 | transducin (beta)-like 2 |
| TRAF4 | TNF receptor-associated factor 4 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TSKS | testis-specific serine kinase substrate |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| XAF1 | XIAP associated factor 1 |
| YIPF4 | Yip1 domain family, member 4 |
| ZNF334 | zinc finger protein 334 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AK5 | adenylate kinase 5 |
| ALPP | alkaline phosphatase, placental |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARMC6 | armadillo repeat containing 6 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CA11 | carbonic anhydrase XI |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP41 | centrosomal protein 41kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CIDEC | cell death-inducing DFFA-like effector c |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CORO2A | coronin, actin binding protein, 2A |
| CORT | cortistatin |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYBRD1 | cytochrome b reductase 1 |
| DDN | dendrin |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DYM | dymeclin |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EFNA3 | ephrin-A3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FGL1 | fibrinogen-like 1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GMPR | guanosine monophosphate reductase |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| HIST1H2BM | histone cluster 1, H2bm |
| HLX | H2.0-like homeobox |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXB9 | homeobox B9 |
| HOXC10 | homeobox C10 |
| HOXC11 | homeobox C11 |
| HPN | hepsin |
| IFT54 | intraflagellar transport 54 |
| IL2 | interleukin 2 |
| INE1 | inactivation escape 1 (non-protein coding) |
| KIAA1549L | KIAA1549-like |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC61 | leucine rich repeat containing 61 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MCOLN1 | mucolipin 1 |
| METRN | meteorin, glial cell differentiation regulator |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| NINJ1 | ninjurin 1 |
| NKX3-2 | NK3 homeobox 2 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| ODF2 | outer dense fiber of sperm tails 2 |
| OLFML2B | olfactomedin-like 2B |
| OSMR | oncostatin M receptor |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PAX9 | paired box 9 |
| PDZK1 | PDZ domain containing 1 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PRSS22 | protease, serine, 22 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RASAL2 | RAS protein activator like 2 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RGCC | regulator of cell cycle |
| RNF146 | ring finger protein 146 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMO | smoothened, frizzled class receptor |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPEG | SPEG complex locus |
| STK16 | serine/threonine kinase 16 |
| STK25 | serine/threonine kinase 25 |
| SUSD4 | sushi domain containing 4 |
| TAOK1 | TAO kinase 1 |
| TCP10 | t-complex 10 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TEX15 | testis expressed 15 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM159 | transmembrane protein 159 |
| TRAC | T cell receptor alpha constant |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF304 | zinc finger protein 304 |
| ZNF446 | zinc finger protein 446 |
| ZNF492 | zinc finger protein 492 |
| ZNF573 | zinc finger protein 573 |
| ZNF816 | zinc finger protein 816 |
