| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the demeclocycline-4267 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| C14ORF105 | chromosome 14 open reading frame 105 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CALB2 | calbindin 2 |
| CARD10 | caspase recruitment domain family, member 10 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD1A | CD1a molecule |
| CD52 | CD52 molecule |
| CD6 | CD6 molecule |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CDON | cell adhesion associated, oncogene regulated |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CLCA1 | chloride channel accessory 1 |
| CNN1 | calponin 1, basic, smooth muscle |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DOK4 | docking protein 4 |
| DSPP | dentin sialophosphoprotein |
| DUOX1 | dual oxidase 1 |
| EPN1 | epsin 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGF6 | fibroblast growth factor 6 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPC3 | glypican 3 |
| GPX5 | glutathione peroxidase 5 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRK5 | G protein-coupled receptor kinase 5 |
| GRM4 | glutamate receptor, metabotropic 4 |
| HCFC1 | host cell factor C1 |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| HOXB7 | homeobox B7 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| ICAM1 | intercellular adhesion molecule 1 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IPO8 | importin 8 |
| IRF4 | interferon regulatory factor 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| JUND | jun D proto-oncogene |
| KALRN | kalirin, RhoGEF kinase |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KSR1 | kinase suppressor of ras 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MGAT4C | MGAT4 family, member C |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NCOR2 | nuclear receptor corepressor 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NRG1 | neuregulin 1 |
| NTN1 | netrin 1 |
| OGFR | opioid growth factor receptor |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLIN2 | perilipin 2 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RGCC | regulator of cell cycle |
| RIMBP2 | RIMS binding protein 2 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| SFTPB | surfactant protein B |
| SH2D1A | SH2 domain containing 1A |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 |
| SMPX | small muscle protein, X-linked |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPRR1A | small proline-rich protein 1A |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYNDIG1 | synapse differentiation inducing 1 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TRA | T cell receptor alpha locus |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| TRIM3 | tripartite motif containing 3 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF549 | zinc finger protein 549 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ANAPC10 | anaphase promoting complex subunit 10 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BEX1 | brain expressed, X-linked 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1R | complement component 1, r subcomponent |
| CDC73 | cell division cycle 73 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CEP112 | centrosomal protein 112kDa |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FAM169A | family with sequence similarity 169, member A |
| FBXO46 | F-box protein 46 |
| FBXO5 | F-box protein 5 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FMO4 | flavin containing monooxygenase 4 |
| GPALPP1 | GPALPP motifs containing 1 |
| GPATCH3 | G patch domain containing 3 |
| H2AFJ | H2A histone family, member J |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H4C | histone cluster 1, H4c |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| LGMN | legumain |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAGEA6 | melanoma antigen family A6 |
| MAGEH1 | melanoma antigen family H1 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MCM9 | minichromosome maintenance complex component 9 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MXD3 | MAX dimerization protein 3 |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit |
| NABP1 | nucleic acid binding protein 1 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OTUD3 | OTU deubiquitinase 3 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PDZK1 | PDZ domain containing 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PSKH1 | protein serine kinase H1 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RFX7 | regulatory factor X, 7 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RRAGB | Ras-related GTP binding B |
| S100A4 | S100 calcium binding protein A4 |
| SEC61B | Sec61 beta subunit |
| SERINC5 | serine incorporator 5 |
| SFT2D2 | SFT2 domain containing 2 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SMAD5 | SMAD family member 5 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SNX16 | sorting nexin 16 |
| SPRYD7 | SPRY domain containing 7 |
| SRSF11 | serine/arginine-rich splicing factor 11 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TESK1 | testis-specific kinase 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TFB1M | transcription factor B1, mitochondrial |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TRABD | TraB domain containing |
| TRAPPC2L | trafficking protein particle complex 2-like |
| TWISTNB | TWIST neighbor |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| WDR3 | WD repeat domain 3 |
| WDR43 | WD repeat domain 43 |
| WWC2 | WW and C2 domain containing 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF273 | zinc finger protein 273 |
| ZNF529 | zinc finger protein 529 |
| ZNF667 | zinc finger protein 667 |
| ZNF813 | zinc finger protein 813 |
