| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the demeclocycline-4728 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AHCYL1 | adenosylhomocysteinase-like 1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CALCA | calcitonin-related polypeptide alpha |
| CPA4 | carboxypeptidase A4 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DVL3 | dishevelled segment polarity protein 3 |
| EDN1 | endothelin 1 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EMID1 | EMI domain containing 1 |
| ESR1 | estrogen receptor 1 |
| EXOSC2 | exosome component 2 |
| FAM46C | family with sequence similarity 46, member C |
| FCGBP | Fc fragment of IgG binding protein |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FOXG1 | forkhead box G1 |
| FRMD4A | FERM domain containing 4A |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPR21 | G protein-coupled receptor 21 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HPX | hemopexin |
| HRASLS2 | HRAS-like suppressor 2 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IRF4 | interferon regulatory factor 4 |
| ITM2C | integral membrane protein 2C |
| KHK | ketohexokinase (fructokinase) |
| KRT24 | keratin 24, type I |
| KRT75 | keratin 75, type II |
| LEFTY2 | left-right determination factor 2 |
| LMNA | lamin A/C |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| MAPK11 | mitogen-activated protein kinase 11 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MYL10 | myosin, light chain 10, regulatory |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) |
| NFIB | nuclear factor I/B |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NPY4R | neuropeptide Y receptor Y4 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
| NRF1 | nuclear respiratory factor 1 |
| OMG | oligodendrocyte myelin glycoprotein |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE10A | phosphodiesterase 10A |
| PENK | proenkephalin |
| PICK1 | protein interacting with PRKCA 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RAB33A | RAB33A, member RAS oncogene family |
| RARA | retinoic acid receptor, alpha |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBP4 | retinol binding protein 4, plasma |
| RSG1 | REM2 and RAB-like small GTPase 1 |
| RSU1 | Ras suppressor protein 1 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC26A1 | solute carrier family 26 (anion exchanger), member 1 |
| SMYD2 | SET and MYND domain containing 2 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SRCAP | Snf2-related CREBBP activator protein |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TBC1D2 | TBC1 domain family, member 2 |
| TBL2 | transducin (beta)-like 2 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRAPPC9 | trafficking protein particle complex 9 |
| TREX1 | three prime repair exonuclease 1 |
| TRIM48 | tripartite motif containing 48 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| VPREB3 | pre-B lymphocyte 3 |
| WAS | Wiskott-Aldrich syndrome |
| WSB1 | WD repeat and SOCS box containing 1 |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| AFAP1 | actin filament associated protein 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| B9D2 | B9 protein domain 2 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC6 | coiled-coil domain containing 6 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD82 | CD82 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CENPJ | centromere protein J |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CSTA | cystatin A (stefin A) |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DIXDC1 | DIX domain containing 1 |
| DMTN | dematin actin binding protein |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EXOC5 | exocyst complex component 5 |
| FAM120C | family with sequence similarity 120C |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FKBP5 | FK506 binding protein 5 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GLRA1 | glycine receptor, alpha 1 |
| HDAC11 | histone deacetylase 11 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4F | histone cluster 1, H4f |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IPO8 | importin 8 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA1456 | KIAA1456 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LMNB1 | lamin B1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MYO1E | myosin IE |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOL12 | nucleolar protein 12 |
| ONECUT1 | one cut homeobox 1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PARD6B | par-6 family cell polarity regulator beta |
| PCDHA5 | protocadherin alpha 5 |
| PCDHB13 | protocadherin beta 13 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PRPH | peripherin |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAI2 | retinoic acid induced 2 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RFXAP | regulatory factor X-associated protein |
| RNF121 | ring finger protein 121 |
| RNF2 | ring finger protein 2 |
| RPA4 | replication protein A4, 30kDa |
| S100A2 | S100 calcium binding protein A2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPRYD7 | SPRY domain containing 7 |
| STK16 | serine/threonine kinase 16 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TESK1 | testis-specific kinase 1 |
| TIGD6 | tigger transposable element derived 6 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| ZNF124 | zinc finger protein 124 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF16 | zinc finger protein 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF253 | zinc finger protein 253 |
| ZNF286A | zinc finger protein 286A |
| ZNF552 | zinc finger protein 552 |
| ZNF586 | zinc finger protein 586 |
| ZNF675 | zinc finger protein 675 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
