demethylation Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The process of removing one or more methyl groups from a molecule. (Gene Ontology, GO_0070988)
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Genes

170 genes co-occuring with the biological term demethylation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACVRL1 activin A receptor type II-like 1
AICDA activation-induced cytidine deaminase
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALKBH5 AlkB family member 5, RNA demethylase
ALOX15 arachidonate 15-lipoxygenase
APC adenomatous polyposis coli
AR androgen receptor
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD7 bromodomain containing 7
C1GALT1C1 C1GALT1-specific chaperone 1
CASR calcium-sensing receptor
CCND1 cyclin D1
CCND2 cyclin D2
CD40LG CD40 ligand
CD70 CD70 molecule
CD8A CD8a molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDX1 caudal type homeobox 1
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
CRABP2 cellular retinoic acid binding protein 2
CRHR2 corticotropin releasing hormone receptor 2
CSAG2 CSAG family, member 2
CTCFL CCCTC-binding factor (zinc finger protein)-like
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
DACT1 dishevelled-binding antagonist of beta-catenin 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOT1L DOT1-like histone H3K79 methyltransferase
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EPAS1 endothelial PAS domain protein 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAS Fas cell surface death receptor
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FKBP5 FK506 binding protein 5
FMR1 fragile X mental retardation 1
FOXA1 forkhead box A1
FOXP3 forkhead box P3
FTO fat mass and obesity associated
GADD45A growth arrest and DNA-damage-inducible, alpha
GP6 glycoprotein VI (platelet)
GRM1 glutamate receptor, metabotropic 1
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HDAC1 histone deacetylase 1
HES1 hes family bHLH transcription factor 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1E histone cluster 1, H1e
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HOXA1 homeobox A1
HOXB4 homeobox B4
HR hair growth associated
IDO1 indoleamine 2,3-dioxygenase 1
IFITM3 interferon induced transmembrane protein 3
IFNG interferon, gamma
IGF2 insulin-like growth factor 2
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL6 interleukin 6
ING1 inhibitor of growth family, member 1
INS insulin
KAT7 K(lysine) acetyltransferase 7
KDM1A lysine (K)-specific demethylase 1A
KDM2A lysine (K)-specific demethylase 2A
KDM3A lysine (K)-specific demethylase 3A
KDM4A lysine (K)-specific demethylase 4A
KDM4C lysine (K)-specific demethylase 4C
KDM5A lysine (K)-specific demethylase 5A
KDM5B lysine (K)-specific demethylase 5B
KDM6A lysine (K)-specific demethylase 6A
KDM6B lysine (K)-specific demethylase 6B
KEAP1 kelch-like ECH-associated protein 1
KIAA0226L KIAA0226-like
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLF10 Kruppel-like factor 10
LEP leptin
MAGEA1 melanoma antigen family A1
MAGEA3 melanoma antigen family A3
MAGEB2 melanoma antigen family B2
MAP2 microtubule-associated protein 2
MAPT microtubule-associated protein tau
MBD3 methyl-CpG binding domain protein 3
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MIR126 microRNA 126
MIR128-1 microRNA 128-1
MIR140 microRNA 140
MIR148B microRNA 148b
MIR152 microRNA 152
MIR17HG miR-17-92 cluster host gene
MIR193A microRNA 193a
MIR29A microRNA 29a
MIR29B1 microRNA 29b-1
MIR29C microRNA 29c
MIR34B microRNA 34b
MIR9-3 microRNA 9-3
MLH1 mutL homolog 1
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MT-ND2 MTND2
MTAP methylthioadenosine phosphorylase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC2 mucin 2, oligomeric mucus/gel-forming
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NANOG Nanog homeobox
NOS2 nitric oxide synthase 2, inducible
NR1H3 nuclear receptor subfamily 1, group H, member 3
PADI4 peptidyl arginine deiminase, type IV
PDCD1 programmed cell death 1
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PGK2 phosphoglycerate kinase 2
PLCD1 phospholipase C, delta 1
POU5F1 POU class 5 homeobox 1
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRF1 perforin 1 (pore forming protein)
PRMT5 protein arginine methyltransferase 5
PROM1 prominin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RARB retinoic acid receptor, beta
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCOR1 REST corepressor 1
RHOA ras homolog family member A
RNF4 ring finger protein 4
SBSN suprabasin
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SET SET nuclear proto-oncogene
SETDB1 SET domain, bifurcated 1
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOCS1 suppressor of cytokine signaling 1
SOX2 SRY (sex determining region Y)-box 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPI1 Spi-1 proto-oncogene
SRCAP Snf2-related CREBBP activator protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TARID TCF21 antisense RNA inducing promoter demethylation
TCF21 transcription factor 21
TDG thymine-DNA glycosylase
TERT telomerase reverse transcriptase
TET1 tet methylcytosine dioxygenase 1
TET2 tet methylcytosine dioxygenase 2
TET3 tet methylcytosine dioxygenase 3
TGFB1 transforming growth factor, beta 1
TLR3 toll-like receptor 3
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOX thymocyte selection-associated high mobility group box
TP53 tumor protein p53
TP73 tumor protein p73
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VAV1 vav 1 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFC vascular endothelial growth factor C
WIF1 WNT inhibitory factor 1