dendritic spine Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity. (Gene Ontology, GO_0043197)
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Genes

506 proteins co-occuring with the dendritic spine cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 2.32881
GRIA1 glutamate receptor, ionotropic, AMPA 1 2.25893
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 2.0736
SHANK3 SH3 and multiple ankyrin repeat domains 3 1.9855
PPP1R9B protein phosphatase 1, regulatory subunit 9B 1.95372
DBN1 drebrin 1 1.86143
BDNF brain-derived neurotrophic factor 1.85113
HOMER1 homer scaffolding protein 1 1.84634
DLG3 discs, large homolog 3 (Drosophila) 1.82592
DLG1 discs, large homolog 1 (Drosophila) 1.72995
PSD pleckstrin and Sec7 domain containing 1.71001
DLG4 discs, large homolog 4 (Drosophila) 1.68482
SHANK1 SH3 and multiple ankyrin repeat domains 1 1.66659
TJP1 tight junction protein 1 1.66357
FMR1 fragile X mental retardation 1 1.64793
SHANK2 SH3 and multiple ankyrin repeat domains 2 1.60651
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.52259
GUK1 guanylate kinase 1 1.52202
SYP synaptophysin 1.48475
GRM5 glutamate receptor, metabotropic 5 1.45986
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.42993
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 1.40131
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 1.37796
GRM1 glutamate receptor, metabotropic 1 1.3752
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.37409
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.37409
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.37354
GPHN gephyrin 1.28783
GRIP1 glutamate receptor interacting protein 1 1.25864
LRRC7 leucine rich repeat containing 7 1.25285
ARC activity-regulated cytoskeleton-associated protein 1.19726
SYNPO synaptopodin 1.188
NRGN neurogranin (protein kinase C substrate, RC3) 1.18184
GRIA4 glutamate receptor, ionotropic, AMPA 4 1.17619
PVALB parvalbumin 1.17158
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.12654
HOMER2 homer scaffolding protein 2 1.12041
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 1.11786
PICK1 protein interacting with PRKCA 1 1.10562
SYN1 synapsin I 1.07613
NLGN1 neuroligin 1 1.07613
CALB1 calbindin 1, 28kDa 1.07562
TH tyrosine hydroxylase 1.06144
OPHN1 oligophrenin 1 1.05942
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.05085
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.04532
RELN reelin 1.03378
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 1.03279
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 1.03029
BAIAP2 BAI1-associated protein 2 1.0104
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 1.00645
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 1.00645
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.996613
EPHB3 EPH receptor B3 0.985367
ITPKA inositol-trisphosphate 3-kinase A 0.980016
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.97178
RAP1GAP RAP1 GTPase activating protein 0.963588
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.959268
CREB1 cAMP responsive element binding protein 1 0.955917
EPHA4 EPH receptor A4 0.949713
NLGN2 neuroligin 2 0.913443
EPHB2 EPH receptor B2 0.913443
STRN striatin, calmodulin binding protein 0.911579
CDK5 cyclin-dependent kinase 5 0.905531
PISD phosphatidylserine decarboxylase 0.899499
NEXN nexilin (F actin binding protein) 0.894868
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.888859
FYN FYN proto-oncogene, Src family tyrosine kinase 0.885166
CABP1 calcium binding protein 1 0.880555
MAP2 microtubule-associated protein 2 0.878712
MEA1 male-enhanced antigen 1 0.876409
CRIPT cysteine-rich PDZ-binding protein 0.868126
KALRN kalirin, RhoGEF kinase 0.864447
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.852961
CTNND2 catenin (cadherin-associated protein), delta 2 0.846991
CTTN cortactin 0.844696
STRN4 striatin, calmodulin binding protein 4 0.841023
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.835515
ACTN2 actinin, alpha 2 0.831843
MECP2 methyl CpG binding protein 2 0.830925
ICAM5 intercellular adhesion molecule 5, telencephalin 0.825877
CDC42 cell division cycle 42 0.8245
APP amyloid beta (A4) precursor protein 0.82037
BSN bassoon presynaptic cytomatrix protein 0.813028
GRIK1 glutamate receptor, ionotropic, kainate 1 0.813028
ARHGAP32 Rho GTPase activating protein 32 0.809817
RBM10 RNA binding motif protein 10 0.80523
GRID2 glutamate receptor, ionotropic, delta 2 0.800645
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 0.795145
ERBB4 erb-b2 receptor tyrosine kinase 4 0.785529
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.782784
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.778212
DISC1 disrupted in schizophrenia 1 0.776384
CTTNBP2 cortactin binding protein 2 0.75181
PALM paralemmin 0.748189
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.747737
TIAM1 T-cell lymphoma invasion and metastasis 1 0.739614
CHAT choline O-acetyltransferase 0.728389
NRG1 neuregulin 1 0.724365
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.720797
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0.71857
CNR1 cannabinoid receptor 1 (brain) 0.715014
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.712795
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.702626
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.702185
NLGN3 neuroligin 3 0.699103
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.696465
IQSEC2 IQ motif and Sec7 domain 2 0.69164
CALB2 calbindin 2 0.689888
DNM3 dynamin 3 0.689888
MYO5A myosin VA (heavy chain 12, myoxin) 0.68508
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 0.684207
OPRM1 opioid receptor, mu 1 0.678978
MPDZ multiple PDZ domain protein 0.662503
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.656895
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.656464
NTNG1 netrin G1 0.651299
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.64915
SST somatostatin 0.647433
NCKIPSD NCK interacting protein with SH3 domain 0.640145
GAP43 growth associated protein 43 0.638434
MAPT microtubule-associated protein tau 0.63715
TAC1 tachykinin, precursor 1 0.631171
NGEF neuronal guanine nucleotide exchange factor 0.627761
EMX1 empty spiracles homeobox 1 0.623504
TRAPPC4 trafficking protein particle complex 4 0.621804
GDA guanine deaminase 0.614589
CRHR1 corticotropin releasing hormone receptor 1 0.613742
BAIAP2L1 BAI1-associated protein 2-like 1 0.613742
CRH corticotropin releasing hormone 0.613742
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.613318
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 0.60655
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.606128
DRD2 dopamine receptor D2 0.60444
SRCIN1 SRC kinase signaling inhibitor 1 0.60444
SDCBP2 syndecan binding protein (syntenin) 2 0.601487
SYNGAP1 synaptic Ras GTPase activating protein 1 0.599802
ESR1 estrogen receptor 1 0.598538
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 0.596855
NGFR nerve growth factor receptor 0.594753
HIST1H2BJ histone cluster 1, H2bj 0.592652
BEGAIN brain-enriched guanylate kinase-associated 0.583012
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.580922
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 0.580922
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.580504
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 0.580086
SHARPIN SHANK-associated RH domain interactor 0.579669
NRP2 neuropilin 2 0.579251
ZC4H2 zinc finger, C4H2 domain containing 0.575495
PRR7 proline rich 7 (synaptic) 0.575495
ZDHHC8 zinc finger, DHHC-type containing 8 0.574244
DCX doublecortin 0.573411
PDZK1 PDZ domain containing 1 0.572994
PDLIM5 PDZ and LIM domain 5 0.571329
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 0.570496
RGS7BP regulator of G-protein signaling 7 binding protein 0.568001
PRICKLE2 prickle homolog 2 (Drosophila) 0.563017
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 0.562602
PLK2 polo-like kinase 2 0.562187
ARF6 ADP-ribosylation factor 6 0.562187
PALMD palmdelphin 0.559285
DNM2 dynamin 2 0.557629
ADGRL3 adhesion G protein-coupled receptor L3 0.5568
LIN7A lin-7 homolog A (C. elegans) 0.553078
RTN4R reticulon 4 receptor 0.54936
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 0.545648
ASIC1 acid sensing (proton gated) ion channel 1 0.544
CA1 carbonic anhydrase I 0.539883
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.538649
CBLN1 cerebellin 1 precursor 0.536594
NTNG2 netrin G2 0.529618
SDC2 syndecan 2 0.527979
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.525931
PALM2 paralemmin 2 0.525113
PALM2-AKAP2 PALM2-AKAP2 readthrough 0.525113
PALM3 paralemmin 3 0.525113
EPS8 epidermal growth factor receptor pathway substrate 8 0.523476
INA internexin neuronal intermediate filament protein, alpha 0.521432
NGF nerve growth factor (beta polypeptide) 0.51327
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.512862
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.50757
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.503912
PSEN1 presenilin 1 0.502693
NLGN4X neuroligin 4, X-linked 0.499853
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.499042
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.499042
GNG7 guanine nucleotide binding protein (G protein), gamma 7 0.499042
DAGLA diacylglycerol lipase, alpha 0.49742
RTN4 reticulon 4 0.493775
GRIK2 glutamate receptor, ionotropic, kainate 2 0.492157
ANK1 ankyrin 1, erythrocytic 0.488519
HOMER3 homer scaffolding protein 3 0.488115
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 0.487711
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 0.487307
EFNA3 ephrin-A3 0.485693
MAP1A microtubule-associated protein 1A 0.482064
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.48005
CDH7 cadherin 7, type 2 0.478038
SLITRK5 SLIT and NTRK-like family, member 5 0.470406
CPEB3 cytoplasmic polyadenylation element binding protein 3 0.4672
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.466799
AKAP5 A kinase (PRKA) anchor protein 5 0.466399
GJD2 gap junction protein, delta 2, 36kDa 0.465198
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.464397
ARHGAP35 Rho GTPase activating protein 35 0.463598
CDH19 cadherin 19, type 2 0.462398
GRM2 glutamate receptor, metabotropic 2 0.458006
CDKL5 cyclin-dependent kinase-like 5 0.456809
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.456809
FOS FBJ murine osteosarcoma viral oncogene homolog 0.452825
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 0.449245
DMD dystrophin 0.446862
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.440916
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 0.440124
NRXN1 neurexin 1 0.439333
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.438542
ADGRB1 adhesion G protein-coupled receptor B1 0.438146
ISL1 ISL LIM homeobox 1 0.438146
ARHGAP39 Rho GTPase activating protein 39 0.437751
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 0.437356
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.43696
CTBP2 C-terminal binding protein 2 0.432618
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.432224
MOB4 MOB family member 4, phocein 0.430647
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.430647
ARHGAP44 Rho GTPase activating protein 44 0.430253
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.429072
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.429072
DTNBP1 dystrobrevin binding protein 1 0.424745
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 0.424353
DGKB diacylglycerol kinase, beta 90kDa 0.423567
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.422782
CRIPAK cysteine-rich PAK1 inhibitor 0.421997
TARP TCR gamma alternate reading frame protein 0.420036
TPH1 tryptophan hydroxylase 1 0.419252
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 0.414555
UBE3A ubiquitin protein ligase E3A 0.412992
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 0.410259
MIR190A microRNA 190a 0.409869
ARHGAP18 Rho GTPase activating protein 18 0.408699
STARD13 StAR-related lipid transfer (START) domain containing 13 0.40675
SCRIB scribbled planar cell polarity protein 0.405582
RNASE13 ribonuclease, RNase A family, 13 (non-active) 0.398587
CA13 carbonic anhydrase XIII 0.397423
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.39626
SDCBP syndecan binding protein (syntenin) 0.392388
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.392388
FXR2 fragile X mental retardation, autosomal homolog 2 0.392388
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 0.392001
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.391615
LRRTM1 leucine rich repeat transmembrane neuronal 1 0.391228
NSF N-ethylmaleimide-sensitive factor 0.390841
ESR2 estrogen receptor 2 (ER beta) 0.383895
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.383509
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.383124
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.382354
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 0.381199
NCAM1 neural cell adhesion molecule 1 0.378507
NRCAM neuronal cell adhesion molecule 0.375818
PTCHD1 patched domain containing 1 0.375434
MYEF2 myelin expression factor 2 0.373516
PTPRD protein tyrosine phosphatase, receptor type, D 0.37045
RAP1GAP2 RAP1 GTPase activating protein 2 0.370067
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 0.369301
LRRC4C leucine rich repeat containing 4C 0.368919
SSTR4 somatostatin receptor 4 0.367388
LRRC4 leucine rich repeat containing 4 0.365477
FBXO33 F-box protein 33 0.363949
DYNLL2 dynein, light chain, LC8-type 2 0.362804
LZTS2 leucine zipper, putative tumor suppressor 2 0.361659
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.360515
PENK proenkephalin 0.360133
MARCKS myristoylated alanine-rich protein kinase C substrate 0.35899
HTT huntingtin 0.358609
SEZ6 seizure related 6 homolog (mouse) 0.358228
CADM1 cell adhesion molecule 1 0.352901
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.351382
AKAP1 A kinase (PRKA) anchor protein 1 0.347967
ZDHHC2 zinc finger, DHHC-type containing 2 0.346071
DLG2 discs, large homolog 2 (Drosophila) 0.343799
PLEK pleckstrin 0.343799
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.341907
TLL1 tolloid-like 1 0.341529
PDYN prodynorphin 0.341151
MIR212 microRNA 212 0.340773
ADGRL2 adhesion G protein-coupled receptor L2 0.340395
NCR3 natural cytotoxicity triggering receptor 3 0.338884
VASP vasodilator-stimulated phosphoprotein 0.336996
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.333979
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.332472
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.331342
SRR serine racemase 0.329084
PCDH11Y protocadherin 11 Y-linked 0.328332
WAS Wiskott-Aldrich syndrome 0.328332
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.327956
NTN1 netrin 1 0.326829
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.326453
ABI2 abl-interactor 2 0.326078
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.326078
MAP4 microtubule-associated protein 4 0.325327
MMP9 matrix metallopeptidase 9 0.324201
PDE10A phosphodiesterase 10A 0.323825
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.323825
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.32195
SEPT7 septin 7 0.321201
PNMT phenylethanolamine N-methyltransferase 0.320826
PCDH11X protocadherin 11 X-linked 0.320451
GOPC golgi-associated PDZ and coiled-coil motif containing 0.318579
ADD1 adducin 1 (alpha) 0.316334
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.315586
PFN2 profilin 2 0.315586
SNTA1 syntrophin, alpha 1 0.314465
CUX2 cut-like homeobox 2 0.312971
ADAT3 adenosine deaminase, tRNA-specific 3 0.312971
CTTNBP2NL CTTNBP2 N-terminal like 0.311478
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.309986
BTBD3 BTB (POZ) domain containing 3 0.307749
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.307377
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.30626
NPY neuropeptide Y 0.305888
ABI3 ABI family, member 3 0.305515
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.302912
PFN1 profilin 1 0.302168
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.302168
ACTBL2 actin, beta-like 2 0.301797
ITGA8 integrin, alpha 8 0.301425
ZMYND19 zinc finger, MYND-type containing 19 0.300311
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 0.299197
RTN4RL2 reticulon 4 receptor-like 2 0.298826
GRM3 glutamate receptor, metabotropic 3 0.297713
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.297342
PSD2 pleckstrin and Sec7 domain containing 2 0.296972
PDZD3 PDZ domain containing 3 0.294007
PTK2B protein tyrosine kinase 2 beta 0.294007
CALY calcyon neuron-specific vesicular protein 0.293637
VEZT vezatin, adherens junctions transmembrane protein 0.292897
EFNB1 ephrin-B1 0.292897
PLXNA3 plexin A3 0.291047
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.285876
GRM4 glutamate receptor, metabotropic 4 0.285138
NRN1 neuritin 1 0.284032
INADL InaD-like (Drosophila) 0.281085
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.278877
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 0.276671
KIRREL2 kin of IRRE like 2 (Drosophila) 0.275569
LIMK1 LIM domain kinase 1 0.275202
CKAP4 cytoskeleton-associated protein 4 0.274835
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive 0.272267
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 0.270434
CCK cholecystokinin 0.270434
GSK3B glycogen synthase kinase 3 beta 0.269701
APOE apolipoprotein E 0.264946
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.261296
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.260931
EZR ezrin 0.260566
UBA6 ubiquitin-like modifier activating enzyme 6 0.259837
SERF1B small EDRK-rich factor 1B (centromeric) 0.259109
SERF1A small EDRK-rich factor 1A (telomeric) 0.259109
ARHGAP33 Rho GTPase activating protein 33 0.258016
APLP1 amyloid beta (A4) precursor-like protein 1 0.257289
NTF3 neurotrophin 3 0.25547
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.255107
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.254743
ASIC3 acid sensing (proton gated) ion channel 3 0.25438
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.254017
DBX1 developing brain homeobox 1 0.254017
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.254017
IQSEC3 IQ motif and Sec7 domain 3 0.253291
SEPT6 septin 6 0.252564
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 0.251476
PKN1 protein kinase N1 0.250751
TBKBP1 TBK1 binding protein 1 0.249664
ITPKB inositol-trisphosphate 3-kinase B 0.249302
ADAM10 ADAM metallopeptidase domain 10 0.24894
KLHL17 kelch-like family member 17 0.248578
NTS neurotensin 0.247854
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.247854
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.247492
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 0.246407
CORT cortistatin 0.246046
DICER1 dicer 1, ribonuclease type III 0.244962
PHF1 PHD finger protein 1 0.244962
KARS lysyl-tRNA synthetase 0.242797
VANGL2 VANGL planar cell polarity protein 2 0.238478
KIDINS220 kinase D-interacting substrate, 220kDa 0.238478
AMPH amphiphysin 0.238119
HUNK hormonally up-regulated Neu-associated kinase 0.237042
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.236683
TRIM11 tripartite motif containing 11 0.236324
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 0.235607
MORN4 MORN repeat containing 4 0.235607
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 0.233459
EPB41 erythrocyte membrane protein band 4.1 0.233101
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 0.232029
NPS neuropeptide S 0.231672
SEPT5 septin 5 0.231315
UTRN utrophin 0.228464
LYPLA1 lysophospholipase I 0.226686
TMEM245 transmembrane protein 245 0.226686
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.224204
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 0.223143
SHISA9 shisa family member 9 0.22279
PFN4 profilin family, member 4 0.219617
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.219617
ACHE acetylcholinesterase (Yt blood group) 0.218563
GFAP glial fibrillary acidic protein 0.217511
AIF1 allograft inflammatory factor 1 0.21716
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.21646
ACD adrenocortical dysplasia homolog (mouse) 0.215063
NEUROD4 neuronal differentiation 4 0.215063
HPCA hippocalcin 0.213322
IL16 interleukin 16 0.212974
DRD1 dopamine receptor D1 0.211587
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 0.211587
ZNF804A zinc finger protein 804A 0.210894
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 0.210203
TBL1X transducin (beta)-like 1X-linked 0.209858
MPHOSPH9 M-phase phosphoprotein 9 0.209858
DGKZ diacylglycerol kinase, zeta 0.209513
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.208825
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 0.207794
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.206082
ATXN1 ataxin 1 0.20574
CPEB2 cytoplasmic polyadenylation element binding protein 2 0.20574
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 0.205399
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.205399
SDF4 stromal cell derived factor 4 0.204039
TTYH1 tweety family member 1 0.203361
GPR88 G protein-coupled receptor 88 0.202684
ADAM22 ADAM metallopeptidase domain 22 0.202684
MGAM maltase-glucoamylase 0.200999
SCX scleraxis basic helix-loop-helix transcription factor 0.200663
CHRM1 cholinergic receptor, muscarinic 1 0.199659
LRFN2 leucine rich repeat and fibronectin type III domain containing 2 0.199659
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.199659
EFNB3 ephrin-B3 0.199659
INSR insulin receptor 0.198658
APC adenomatous polyposis coli 0.197993
DTNB dystrobrevin, beta 0.19733
FUS FUS RNA binding protein 0.19601
CARTPT CART prepropeptide 0.195353
ADRA2A adrenoceptor alpha 2A 0.194698
KIF26B kinesin family member 26B 0.194371
NF1 neurofibromin 1 0.193719
NDEL1 nudE neurodevelopment protein 1-like 1 0.192746
RAB8A RAB8A, member RAS oncogene family 0.192423
AP4M1 adaptor-related protein complex 4, mu 1 subunit 0.191777
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.191456
TOR1A torsin family 1, member A (torsin A) 0.191456
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 0.190814
MAP1B microtubule-associated protein 1B 0.190814
NXN nucleoredoxin 0.190175
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.189539
GHRL ghrelin/obestatin prepropeptide 0.18859
LATS1 large tumor suppressor kinase 1 0.187646
MAPK3 mitogen-activated protein kinase 3 0.185777
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.18516
HIST1H1A histone cluster 1, H1a 0.184241
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 0.183025
THY1 Thy-1 cell surface antigen 0.182422
HDAC9 histone deacetylase 9 0.181823
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.181524
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.181524
UNC13A unc-13 homolog A (C. elegans) 0.180634
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.180634
ACTN1 actinin, alpha 1 0.180045
ARRB1 arrestin, beta 1 0.179459
CA4 carbonic anhydrase IV 0.179459
PTEN phosphatase and tensin homolog 0.179167
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.178588
ADD3 adducin 3 (gamma) 0.177724
TRIM3 tripartite motif containing 3 0.177439
PBK PDZ binding kinase 0.176587
NPTN neuroplastin 0.176305
MARK2 MAP/microtubule affinity-regulating kinase 2 0.175745
CCDC88C coiled-coil domain containing 88C 0.174911
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.174361
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 0.174087
NRXN3 neurexin 3 0.172201
SPTBN2 spectrin, beta, non-erythrocytic 2 0.171673
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.170371
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.170114
SORCS3 sortilin-related VPS10 domain containing receptor 3 0.169859
SLC16A4 solute carrier family 16, member 4 0.16935
WASL Wiskott-Aldrich syndrome-like 0.168598
ARHGAP1 Rho GTPase activating protein 1 0.168598
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 0.168349
CRMP1 collapsin response mediator protein 1 0.165463
GLUD2 glutamate dehydrogenase 2 0.163865
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.163641
DYNLRB1 dynein, light chain, roadblock-type 1 0.163641
PLAT plasminogen activator, tissue 0.161905
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.161484
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.160456
CNIH2 cornichon family AMPA receptor auxiliary protein 2 0.160254
EPHB1 EPH receptor B1 0.159658
HTRA2 HtrA serine peptidase 2 0.159462
IGF1 insulin-like growth factor 1 (somatomedin C) 0.159268
GHSR growth hormone secretagogue receptor 0.158882
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 0.158692
ADGRL1 adhesion G protein-coupled receptor L1 0.157943
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.157218
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.156863
PARD6A par-6 family cell polarity regulator alpha 0.156688
CSN1S1 casein alpha s1 0.14588
CA3 carbonic anhydrase III 0.144446