dengue disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in infection, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted_by Aedes mosquito bite. The infection has_symptom fever, has_symptom severe headache, has_symptom severe pain behind the eyes, has_symptom joint pain, has_symptom muscle and bone pain, has_symptom rash, and has_symptom mild bleeding. (Human Disease Ontology, DOID_12205)
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Genes

243 genes co-occuring with the disease dengue disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.80698
CLEC5A C-type lectin domain family 5, member A 1.6077
PRNT prion protein (testis specific) 1.50886
CD209 CD209 molecule 1.39564
KRAS Kirsten rat sarcoma viral oncogene homolog 1.27693
ERVW-1 endogenous retrovirus group W, member 1 1.23039
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 1.17206
SPAG9 sperm associated antigen 9 1.1473
F3 coagulation factor III (thromboplastin, tissue factor) 1.03746
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.00161
F2 coagulation factor II (thrombin) 1.00035
ATR ATR serine/threonine kinase 1.00035
MICB MHC class I polypeptide-related sequence B 0.996549
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.991065
TNF tumor necrosis factor 0.942858
CXCL10 chemokine (C-X-C motif) ligand 10 0.935385
STAT2 signal transducer and activator of transcription 2, 113kDa 0.902799
THBD thrombomodulin 0.865502
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.840525
HLA-A major histocompatibility complex, class I, A 0.833148
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 0.817565
PLCE1 phospholipase C, epsilon 1 0.814693
HLA-C major histocompatibility complex, class I, C 0.806488
CD4 CD4 molecule 0.789262
AVIL advillin 0.783526
ALB albumin 0.774114
ICAM3 intercellular adhesion molecule 3 0.771252
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.754527
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.747204
OR13F1 olfactory receptor, family 13, subfamily F, member 1 0.730976
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.707157
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.691094
PLG plasminogen 0.687091
IFNA1 interferon, alpha 1 0.671527
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 0.669936
CAPRIN1 cell cycle associated protein 1 0.646559
INTS8 integrator complex subunit 8 0.635921
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.633563
DAXX death-domain associated protein 0.626103
RPS29 ribosomal protein S29 0.622183
STAT1 signal transducer and activator of transcription 1, 91kDa 0.617094
ICAM1 intercellular adhesion molecule 1 0.608885
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.594843
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.582384
ICT1 immature colon carcinoma transcript 1 0.582384
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.578106
C5AR1 complement component 5a receptor 1 0.569941
CCL5 chemokine (C-C motif) ligand 5 0.568775
HPSE2 heparanase 2 (inactive) 0.563723
IL1B interleukin 1, beta 0.563335
IFI6 interferon, alpha-inducible protein 6 0.55945
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.550911
NTSR1 neurotensin receptor 1 (high affinity) 0.545481
RPL14 ribosomal protein L14 0.541992
HLA-B major histocompatibility complex, class I, B 0.538893
IL33R interleukin 33 receptor 0.528835
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.524974
LAMP1 lysosomal-associated membrane protein 1 0.522659
RNMT RNA (guanine-7-) methyltransferase 0.520731
CDH5 cadherin 5, type 2 (vascular endothelium) 0.511496
TKFC triokinase/FMN cyclase 0.506123
A1CF APOBEC1 complementation factor 0.487788
CCL4 chemokine (C-C motif) ligand 4 0.483604
IL10 interleukin 10 0.481705
RAB18 RAB18, member RAS oncogene family 0.479807
VEZF1 vascular endothelial zinc finger 1 0.479807
SCN3A sodium channel, voltage gated, type III alpha subunit 0.476014
KIF5B kinesin family member 5B 0.474119
CPB2 carboxypeptidase B2 (plasma) 0.472604
SERF1B small EDRK-rich factor 1B (centromeric) 0.470332
SERF1A small EDRK-rich factor 1A (telomeric) 0.470332
CD69 CD69 molecule 0.466928
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.463149
CAMKV CaM kinase-like vesicle-associated 0.462394
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.456355
IL6 interleukin 6 0.451831
GLYAT glycine-N-acyltransferase 0.450324
LGALS9 lectin, galactoside-binding, soluble, 9 0.446935
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.442418
SLAMF6 SLAM family member 6 0.438658
CROCC ciliary rootlet coiled-coil, rootletin 0.437906
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.433021
OASL 2'-5'-oligoadenylate synthetase-like 0.431894
MMP24 matrix metallopeptidase 24 (membrane-inserted) 0.431519
IRF3 interferon regulatory factor 3 0.427765
TLR7 toll-like receptor 7 0.423265
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.421765
MAGED1 melanoma antigen family D1 0.420641
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.407545
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.405305
VCAM1 vascular cell adhesion molecule 1 0.404184
CLTC clathrin, heavy chain (Hc) 0.400453
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.397471
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.396353
TJP1 tight junction protein 1 0.392257
CD59 CD59 molecule, complement regulatory protein 0.391885
VEGFA vascular endothelial growth factor A 0.389281
CCL3 chemokine (C-C motif) ligand 3 0.376661
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.376661
TLR3 toll-like receptor 3 0.375179
PLSCR1 phospholipid scramblase 1 0.372958
KDR kinase insert domain receptor 0.370737
ARHGAP35 Rho GTPase activating protein 35 0.360026
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.358183
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.351555
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.351187
CLEC4M C-type lectin domain family 4, member M 0.349717
FAM131C family with sequence similarity 131, member C 0.349717
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.347144
JUP junction plakoglobin 0.342372
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.326281
CD80 CD80 molecule 0.325916
UBA1 ubiquitin-like modifier activating enzyme 1 0.320817
AGO1 argonaute RISC catalytic component 1 0.320454
LIN9 lin-9 DREAM MuvB core complex component 0.319726
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.314278
AHRR aryl-hydrocarbon receptor repressor 0.310652
IL2RA interleukin 2 receptor, alpha 0.307395
CRP C-reactive protein, pentraxin-related 0.305587
P4HB prolyl 4-hydroxylase, beta polypeptide 0.305587
IRF7 interferon regulatory factor 7 0.305587
MX1 MX dynamin-like GTPase 1 0.305226
DMRT1 doublesex and mab-3 related transcription factor 1 0.30342
GDF2 growth differentiation factor 2 0.302698
CD86 CD86 molecule 0.301976
CCL2 chemokine (C-C motif) ligand 2 0.301976
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 0.294772
GBP1 guanylate binding protein 1, interferon-inducible 0.28616
MIER1 mesoderm induction early response 1, transcriptional regulator 0.284013
PF4 platelet factor 4 0.278297
HAND1 heart and neural crest derivatives expressed 1 0.27687
PCDH8 protocadherin 8 0.275801
CD83 CD83 molecule 0.274732
MRC1 mannose receptor, C type 1 0.274021
ANGPTL3 angiopoietin-like 3 0.269753
OPN3 opsin 3 0.267977
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.266203
LTA lymphotoxin alpha 0.258417
IRF9 interferon regulatory factor 9 0.255946
PLAT plasminogen activator, tissue 0.255946
HPX hemopexin 0.255594
VWF von Willebrand factor 0.248554
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.245747
CCL3L1 chemokine (C-C motif) ligand 3-like 1 0.243645
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.241546
EIF5A eukaryotic translation initiation factor 5A 0.240497
MOGS mannosyl-oligosaccharide glucosidase 0.240148
SYT1 synaptotagmin I 0.237706
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.228333
CFB complement factor B 0.227642
IL11 interleukin 11 0.226607
SHF Src homology 2 domain containing F 0.221108
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.221108
TGFB1 transforming growth factor, beta 1 0.218715
ALPP alkaline phosphatase, placental 0.216332
HRG histidine-rich glycoprotein 0.216332
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.215992
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.210589
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.205916
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.201308
PRDX4 peroxiredoxin 4 0.200331
ALPPL2 alkaline phosphatase, placental-like 2 0.199681
ALPL alkaline phosphatase, liver/bone/kidney 0.199033
GC group-specific component (vitamin D binding protein) 0.188938
XAF1 XIAP associated factor 1 0.188632
MICA MHC class I polypeptide-related sequence A 0.188632
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.18472
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 0.182957
RSPO1 R-spondin 1 0.18151
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.181222
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.180937
CLU clusterin 0.179802
CD1D CD1d molecule 0.178126
CARD17 caspase recruitment domain family, member 17 0.176485
NEUROD1 neuronal differentiation 1 0.175146
IL2 interleukin 2 0.173832
IL18BP interleukin 18 binding protein 0.169091
ANXA2 annexin A2 0.165217
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.162109
IRF1 interferon regulatory factor 1 0.161716
DCN decorin 0.161331
ADAR adenosine deaminase, RNA-specific 0.160387
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.158951
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.144365
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.144326
TYROBP TYRO protein tyrosine kinase binding protein 0.143864
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.143711
ISG20 interferon stimulated exonuclease gene 20kDa 0.143629
FXYD1 FXYD domain containing ion transport regulator 1 0.143568
ANGPT2 angiopoietin 2 0.14356
ANGPT1 angiopoietin 1 0.143439
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.143317
FGA fibrinogen alpha chain 0.143076
MMP10 matrix metallopeptidase 10 0.142934
C1S complement component 1, s subcomponent 0.142899
GREM2 gremlin 2, DAN family BMP antagonist 0.142748
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.142673
MMP12 matrix metallopeptidase 12 0.141487
MMP8 matrix metallopeptidase 8 0.139334
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.137262
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.136531
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.136352
IL1RN interleukin 1 receptor antagonist 0.135336
HES5 hes family bHLH transcription factor 5 0.135188
GNLY granulysin 0.134931
PTGIS prostaglandin I2 (prostacyclin) synthase 0.133835
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.133712
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.133444
PTGDR prostaglandin D2 receptor (DP) 0.13326
SELE selectin E 0.132786
PROCR protein C receptor, endothelial 0.132569
LAG3 lymphocyte-activation gene 3 0.132549
JAK1 Janus kinase 1 0.132347
MTDH metadherin 0.132265
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.132057
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.131652
USF2 upstream transcription factor 2, c-fos interacting 0.131608
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.131541
KAT2B K(lysine) acetyltransferase 2B 0.131453
ASCL1 achaete-scute family bHLH transcription factor 1 0.131114
HMGB1 high mobility group box 1 0.131091
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.130976
PLA2G10 phospholipase A2, group X 0.130882
CMA1 chymase 1, mast cell 0.130834
FDPS farnesyl diphosphate synthase 0.130572
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.130524
CD70 CD70 molecule 0.130354
MAP2K1 mitogen-activated protein kinase kinase 1 0.130329
PNMT phenylethanolamine N-methyltransferase 0.130079
TIMP1 TIMP metallopeptidase inhibitor 1 0.130003
MID2 midline 2 0.129483
DYNLT1 dynein, light chain, Tctex-type 1 0.12927
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.128913
CD19 CD19 molecule 0.128715
KIF1B kinesin family member 1B 0.127775
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.127745
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.127715
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.127715
PDGFB platelet-derived growth factor beta polypeptide 0.127623
NOVA2 neuro-oncological ventral antigen 2 0.12731
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.127023
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.126564
ALOX12 arachidonate 12-lipoxygenase 0.126364