dentin Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The calcified tissue below the enamel, enclosing the cavity of the tooth containing the pulp chamber and root canals. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003453)
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Genes

273 proteins co-occuring with the tissue dentin in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
DSPP dentin sialophosphoprotein 3.55063
MEPE matrix extracellular phosphoglycoprotein 2.37443
IBSP integrin-binding sialoprotein 2.35528
AMELX amelogenin, X-linked 2.2909
AMELY amelogenin, Y-linked 2.2577
SPP1 secreted phosphoprotein 1 2.1692
MMD monocyte to macrophage differentiation-associated 2.10859
BGLAP bone gamma-carboxyglutamate (gla) protein 2.08883
DMP1 dentin matrix acidic phosphoprotein 1 2.04444
MMP20 matrix metallopeptidase 20 2.00865
HEBP1 heme binding protein 1 1.93311
PHEX phosphate regulating endopeptidase homolog, X-linked 1.86771
ALPL alkaline phosphatase, liver/bone/kidney 1.84453
ENAM enamelin 1.8281
ALPPL2 alkaline phosphatase, placental-like 2 1.8189
ALPP alkaline phosphatase, placental 1.81685
AMBN ameloblastin (enamel matrix protein) 1.78285
PHF20 PHD finger protein 20 1.6136
FGF23 fibroblast growth factor 23 1.60415
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.50291
RUNX2 runt-related transcription factor 2 1.46961
BMP2 bone morphogenetic protein 2 1.45983
BGN biglycan 1.37727
SHKBP1 SH3KBP1 binding protein 1 1.32596
CSNK2B casein kinase 2, beta polypeptide 1.28457
COL1A1 collagen, type I, alpha 1 1.28367
SP7 Sp7 transcription factor 1.25413
FAM20C family with sequence similarity 20, member C 1.25279
ACPP acid phosphatase, prostate 1.24208
MGAM maltase-glucoamylase 1.2238
MMP2 matrix metallopeptidase 2 1.20778
BMP1 bone morphogenetic protein 1 1.20245
SOST sclerostin 1.194
KCP kielin/chordin-like protein 1.16515
CSN1S1 casein alpha s1 1.15628
NES nestin 1.14343
C3P1 complement component 3 precursor pseudogene 1.13235
FGF7 fibroblast growth factor 7 1.12881
BMP7 bone morphogenetic protein 7 1.12438
HACD1 3-hydroxyacyl-CoA dehydratase 1 1.11995
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.11553
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.11376
MGP matrix Gla protein 1.10314
AMTN amelotin 1.10225
CALCA calcitonin-related polypeptide alpha 1.07485
OMD osteomodulin 1.07309
DCN decorin 1.06294
KLK4 kallikrein-related peptidase 4 1.05677
COL1A2 collagen, type I, alpha 2 1.05633
TBC1D19 TBC1 domain family, member 19 1.04093
TGFB1 transforming growth factor, beta 1 1.04093
CNOT8 CCR4-NOT transcription complex, subunit 8 1.02776
FBLN7 fibulin 7 1.00501
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.99586
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.989335
PTH parathyroid hormone 0.979783
MMP9 matrix metallopeptidase 9 0.963335
C14ORF2 chromosome 14 open reading frame 2 0.962471
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.957722
MCAM melanoma cell adhesion molecule 0.949531
MMP8 matrix metallopeptidase 8 0.940495
BMP4 bone morphogenetic protein 4 0.934911
LYZL2 lysozyme-like 2 0.920771
CA10 carbonic anhydrase X 0.917779
FN1 fibronectin 1 0.908387
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 0.906256
CA6 carbonic anhydrase VI 0.862627
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.859679
MMP25 matrix metallopeptidase 25 0.856732
NOVA2 neuro-oncological ventral antigen 2 0.856312
TUFT1 tuftelin 1 0.85547
NOTCH1 notch 1 0.846225
MMP3 matrix metallopeptidase 3 0.834899
SLC39A13 solute carrier family 39 (zinc transporter), member 13 0.83448
ANGPTL6 angiopoietin-like 6 0.831547
MSX1 msh homeobox 1 0.805213
CEMP1 cementum protein 1 0.801876
TYRP1 tyrosinase-related protein 1 0.801459
KL klotho 0.790212
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.786883
SIX1 SIX homeobox 1 0.783141
GDF11 growth differentiation factor 11 0.782725
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa 0.774834
AHSG alpha-2-HS-glycoprotein 0.767783
SPARCL1 SPARC-like 1 (hevin) 0.757018
PAX9 paired box 9 0.754537
FMOD fibromodulin 0.750405
GFER growth factor, augmenter of liver regeneration 0.745451
SMAD4 SMAD family member 4 0.731031
WNT10A wingless-type MMTV integration site family, member 10A 0.724453
FGF1 fibroblast growth factor 1 (acidic) 0.723631
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.717472
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.717472
SET SET nuclear proto-oncogene 0.717472
MSX2 msh homeobox 2 0.713369
FGF2 fibroblast growth factor 2 (basic) 0.712959
HRAS Harvey rat sarcoma viral oncogene homolog 0.699444
C3ORF18 chromosome 3 open reading frame 18 0.697399
DSP desmoplakin 0.697399
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 0.692085
APEH acylaminoacyl-peptide hydrolase 0.685143
KAT2B K(lysine) acetyltransferase 2B 0.675357
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.663555
ASB2 ankyrin repeat and SOCS box containing 2 0.655836
CTSS cathepsin S 0.65543
LRRC15 leucine rich repeat containing 15 0.653807
SYNC syncoilin, intermediate filament protein 0.644884
APLP1 amyloid beta (A4) precursor-like protein 1 0.61578
VIT vitrin 0.610943
SIX2 SIX homeobox 2 0.610541
IRF6 interferon regulatory factor 6 0.597666
TSPO translocator protein (18kDa) 0.597666
ASPN asporin 0.596862
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 0.595656
LHX6 LIM homeobox 6 0.58322
FAM20B family with sequence similarity 20, member B 0.58242
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.576415
TNC tenascin C 0.575616
CA1 carbonic anhydrase I 0.573616
CDKN2A cyclin-dependent kinase inhibitor 2A 0.572418
HAND1 heart and neural crest derivatives expressed 1 0.57082
CTSK cathepsin K 0.57082
ANKH ANKH inorganic pyrophosphate transport regulator 0.568424
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.567626
MATN2 matrilin 2 0.565631
ALB albumin 0.56284
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.562441
SPTA1 spectrin, alpha, erythrocytic 1 0.552888
DLX5 distal-less homeobox 5 0.539396
TRPV3 transient receptor potential cation channel, subfamily V, member 3 0.537812
PDLIM7 PDZ and LIM domain 7 (enigma) 0.535833
CLDN11 claudin 11 0.523588
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 0.517284
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.516891
MORF4 mortality factor 4 (pseudogene) 0.513743
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.511778
HYLS1 hydrolethalus syndrome 1 0.510599
GPI glucose-6-phosphate isomerase 0.503533
FBL fibrillarin 0.498048
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.494918
MAPK8 mitogen-activated protein kinase 8 0.484376
PCNA proliferating cell nuclear antigen 0.483596
GLRB glycine receptor, beta 0.482817
MMP13 matrix metallopeptidase 13 0.465335
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.464948
SMAD6 SMAD family member 6 0.456828
FOS FBJ murine osteosarcoma viral oncogene homolog 0.454126
FAM20A family with sequence similarity 20, member A 0.452969
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.452969
JUN jun proto-oncogene 0.451813
KRTAP1-3 keratin associated protein 1-3 0.448346
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.446038
KRTAP1-1 keratin associated protein 1-1 0.441042
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.429165
OR1J2 olfactory receptor, family 1, subfamily J, member 2 0.424581
FBLL1 fibrillarin-like 1 0.423818
NGF nerve growth factor (beta polypeptide) 0.419242
TGFBR1 transforming growth factor, beta receptor 1 0.415814
LUM lumican 0.402523
GJA1 gap junction protein, alpha 1, 43kDa 0.402144
PHB2 prohibitin 2 0.401765
PTHLH parathyroid hormone-like hormone 0.400628
TWSG1 twisted gastrulation BMP signaling modulator 1 0.389289
SHF Src homology 2 domain containing F 0.387781
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.385896
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.383637
SLC45A2 solute carrier family 45, member 2 0.382508
MATN4 matrilin 4 0.381755
MANEAL mannosidase, endo-alpha-like 0.379875
KRT14 keratin 14, type I 0.37087
SHH sonic hedgehog 0.37087
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.368624
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 0.367876
ADAM8 ADAM metallopeptidase domain 8 0.366007
PCOLCE procollagen C-endopeptidase enhancer 0.35334
LEF1 lymphoid enhancer-binding factor 1 0.351114
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 0.350001
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.348889
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.348519
NGFR nerve growth factor receptor 0.347778
WNT6 wingless-type MMTV integration site family, member 6 0.342971
SEBOX SEBOX homeobox 0.342233
CLCN5 chloride channel, voltage-sensitive 5 0.341126
BMP6 bone morphogenetic protein 6 0.338914
HSH2D hematopoietic SH2 domain containing 0.338545
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.334865
IPP intracisternal A particle-promoted polypeptide 0.334498
TAC1 tachykinin, precursor 1 0.332661
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.329361
ITM2A integral membrane protein 2A 0.328262
CD44 CD44 molecule (Indian blood group) 0.327896
CES3 carboxylesterase 3 0.327164
ITGAV integrin, alpha V 0.326067
LOX lysyl oxidase 0.323509
HOPX HOP homeobox 0.323144
OGN osteoglycin 0.322779
BANP BTG3 associated nuclear protein 0.321685
SMAD2 SMAD family member 2 0.32132
DLX3 distal-less homeobox 3 0.316951
CEL carboxyl ester lipase 0.316951
NPS neuropeptide S 0.314772
TLR2 toll-like receptor 2 0.312232
PARP15 poly (ADP-ribose) polymerase family, member 15 0.309697
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.307528
GJB4 gap junction protein, beta 4, 30.3kDa 0.307528
GNPDA2 glucosamine-6-phosphate deaminase 2 0.305361
OCM2 oncomodulin 2 0.305361
OCM oncomodulin 0.302118
DLX1 distal-less homeobox 1 0.301398
KDM2B lysine (K)-specific demethylase 2B 0.30032
AXIN2 axin 2 0.297806
DDB1 damage-specific DNA binding protein 1, 127kDa 0.297447
MMP1 matrix metallopeptidase 1 0.293508
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.291722
FLII flightless I homolog (Drosophila) 0.291722
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.289582
MAGEC1 melanoma antigen family C1 0.28887
NANOG Nanog homeobox 0.288158
FHL2 four and a half LIM domains 2 0.287803
DAOA D-amino acid oxidase activator 0.287803
GH2 growth hormone 2 0.284962
PER2 period circadian clock 2 0.284962
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.283899
SOX9 SRY (sex determining region Y)-box 9 0.283545
STPG1 sperm-tail PG-rich repeat containing 1 0.283545
NOG noggin 0.282483
FBLN1 fibulin 1 0.279659
VCAN versican 0.277549
C1ORF174 chromosome 1 open reading frame 174 0.276495
LOXL3 lysyl oxidase-like 3 0.275094
SV2C synaptic vesicle glycoprotein 2C 0.273346
MATN3 matrilin 3 0.272649
CHKA choline kinase alpha 0.271604
ACAN aggrecan 0.271256
TWIST1 twist family bHLH transcription factor 1 0.268482
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.268482
NKX2-3 NK2 homeobox 3 0.264353
PRAMEF9 PRAME family member 9 0.264011
IGF2 insulin-like growth factor 2 0.263669
SENP6 SUMO1/sentrin specific peptidase 6 0.261964
CTNNBIP1 catenin, beta interacting protein 1 0.261624
WAC WW domain containing adaptor with coiled-coil 0.257907
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.25457
HPN hepsin 0.254239
ABR active BCR-related 0.248361
TEX101 testis expressed 101 0.247399
LOXL4 lysyl oxidase-like 4 0.247399
ITSN1 intersectin 1 (SH3 domain protein) 0.246442
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 0.246124
IL1B interleukin 1, beta 0.239913
BEST3 bestrophin 3 0.23961
IGF1 insulin-like growth factor 1 (somatomedin C) 0.239307
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.238406
AJAP1 adherens junctions associated protein 1 0.238108
ODAM odontogenic, ameloblast asssociated 0.237216
PARP14 poly (ADP-ribose) polymerase family, member 14 0.236921
PNMA2 paraneoplastic Ma antigen 2 0.23604
GP5 glycoprotein V (platelet) 0.232881
DNAH8 dynein, axonemal, heavy chain 8 0.232317
ALMS1 Alstrom syndrome protein 1 0.230931
NACA3P NACA family member 3 pseudogene 0.230656
IK IK cytokine, down-regulator of HLA II 0.23011
DNAI1 dynein, axonemal, intermediate chain 1 0.229839
SOX2 SRY (sex determining region Y)-box 2 0.229568
CDNF cerebral dopamine neurotrophic factor 0.228497
SUGP1 SURP and G patch domain containing 1 0.2259
MTF1 metal-regulatory transcription factor 1 0.224645
NOTCH2 notch 2 0.22415
BMP3 bone morphogenetic protein 3 0.222224
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.220831
KLF4 Kruppel-like factor 4 (gut) 0.219928
ADGRE2 adhesion G protein-coupled receptor E2 0.219264
BBS4 Bardet-Biedl syndrome 4 0.217139