denys-drash syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An autosomal dominant disease that is characterized by the association of diffuse mesangial sclerosis (DMS), male pseudohermaphroditism with a 46,XY karyotype, and nephroblastoma that derives_from an abnormality in the WT1 gene (Wilms' tumor suppressor gene). (Human Disease Ontology, DOID_3764)
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Genes

52 genes co-occuring with the disease denys-drash syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
WT1 Wilms tumor 1 2.79541
YIPF2 Yip1 domain family, member 2 1.68
KLF10 Kruppel-like factor 10 1.51237
MECOM MDS1 and EVI1 complex locus 1.47813
ZNF274 zinc finger protein 274 1.36422
SRSF6 serine/arginine-rich splicing factor 6 1.00583
YIPF4 Yip1 domain family, member 4 1.00246
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.991065
SRY sex determining region Y 0.914727
YIPF1 Yip1 domain family, member 1 0.902389
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.865912
PAWR PRKC, apoptosis, WT1, regulator 0.831918
PDGFA platelet-derived growth factor alpha polypeptide 0.815924
ZNF79 zinc finger protein 79 0.769618
SYNPO synaptopodin 0.73746
CD2AP CD2-associated protein 0.71925
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.712392
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.675909
ZNF501 zinc finger protein 501 0.668742
ZNF763 zinc finger protein 763 0.668742
ZNF569 zinc finger protein 569 0.668742
ZNF629 zinc finger protein 629 0.668742
ZNF44 zinc finger protein 44 0.654858
BCL6B B-cell CLL/lymphoma 6, member B 0.638282
AMHR2 anti-Mullerian hormone receptor, type II 0.615529
PAX2 paired box 2 0.579661
IGF2 insulin-like growth factor 2 0.578883
EGR1 early growth response 1 0.578494
HLA-DMA major histocompatibility complex, class II, DM alpha 0.560227
IGFBP4 insulin-like growth factor binding protein 4 0.554791
ZNF436 zinc finger protein 436 0.554015
CCNG1 cyclin G1 0.53657
COL5A1 collagen, type V, alpha 1 0.533861
SDC2 syndecan 2 0.528835
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.523045
AMH anti-Mullerian hormone 0.482844
SCEL sciellin 0.425139
HTN3 histatin 3 0.409787
COL4A4 collagen, type IV, alpha 4 0.403064
SRSF2 serine/arginine-rich splicing factor 2 0.387423
FEN1 flap structure-specific endonuclease 1 0.347879
ACTN4 actinin, alpha 4 0.328105
RFXANK regulatory factor X-associated ankyrin-containing protein 0.32009
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.269398
VEGFA vascular endothelial growth factor A 0.265494
LATS1 large tumor suppressor kinase 1 0.249608
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.247501
SRSF1 serine/arginine-rich splicing factor 1 0.245046
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.238752
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.237706
COL4A5 collagen, type IV, alpha 5 0.201635
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.174354