deoxyhypusine biosynthetic process from spermidine Gene Set
Dataset
GO Biological Process Annotations 2015
Category
structural or functional annotations
Type
biological process
Description
The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+. (Gene Ontology , GO_0050983 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0050983
Similar Terms
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Genes
1 genes participating in the deoxyhypusine biosynthetic process from spermidine biological process from the curated GO Biological Process Annotations 2015 dataset.
Symbol
Name
DHPS
deoxyhypusine synthase
