deoxyhypusine synthase activity Gene Set
| Dataset |
GO Molecular Function Annotations 2023
|
| Category |
structural or functional annotations
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| Type |
biological process |
| Description |
Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+. (Gene Ontology, GO_0034038)
|
| External Link |
http://amigo.geneontology.org/amigo/term/GO:0034038
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| Similar Terms |
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| Downloads & Tools |
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Genes
1 genes performing the deoxyhypusine synthase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.
| Symbol |
Name |
|
DHPS
|
deoxyhypusine synthase
|
