dependence Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

391 genes co-occuring with the biological term dependence in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABLIM1 actin binding LIM protein 1
ADCY7 adenylate cyclase 7
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADPGK ADP-dependent glucokinase
ADRB2 adrenoceptor beta 2, surface
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKR1C3 aldo-keto reductase family 1, member C3
AKR1D1 aldo-keto reductase family 1, member D1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AMPD1 adenosine monophosphate deaminase 1
ANAPC1 anaphase promoting complex subunit 1
ANKK1 ankyrin repeat and kinase domain containing 1
ANO1 anoctamin 1, calcium activated chloride channel
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
ARID1A AT rich interactive domain 1A (SWI-like)
ARID1B AT rich interactive domain 1B (SWI1-like)
ARRB2 arrestin, beta 2
ASIC1 acid sensing (proton gated) ion channel 1
ASPNAT aspartate N-acetyltransferase
ASTN1 astrotactin 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
AUTS2 autism susceptibility candidate 2
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDNF brain-derived neurotrophic factor
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
C3 complement component 3
CABP1 calcium binding protein 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CALY calcyon neuron-specific vesicular protein
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CANX calnexin
CARTPT CART prepropeptide
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD28 CD28 molecule
CD4 CD4 molecule
CD81 CD81 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDNF cerebral dopamine neurotrophic factor
CERK ceramide kinase
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAT choline O-acetyltransferase
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CLCN4 chloride channel, voltage-sensitive 4
CNR1 cannabinoid receptor 1 (brain)
CNTN2 contactin 2 (axonal)
COL18A1 collagen, type XVIII, alpha 1
COL1A2 collagen, type I, alpha 2
COL25A1 collagen, type XXV, alpha 1
COMT catechol-O-methyltransferase
CPB2 carboxypeptidase B2 (plasma)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CSNK1E casein kinase 1, epsilon
CSTB cystatin B (stefin B)
CTGF connective tissue growth factor
CTNNBIP1 catenin, beta interacting protein 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCLRE1C DNA cross-link repair 1C
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DLC1 DLC1 Rho GTPase activating protein
DLG4 discs, large homolog 4 (Drosophila)
DNM1 dynamin 1
DPYSL2 dihydropyrimidinase-like 2
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
DTNBP1 dystrobrevin binding protein 1
DUSP3 dual specificity phosphatase 3
DUSP8 dual specificity phosphatase 8
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ENO2 enolase 2 (gamma, neuronal)
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETF1 eukaryotic translation termination factor 1
EYS eyes shut homolog (Drosophila)
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
FAAH fatty acid amide hydrolase
FAM53B family with sequence similarity 53, member B
FBN1 fibrillin 1
FHL2 four and a half LIM domains 2
FMO1 flavin containing monooxygenase 1
FN1 fibronectin 1
FRMD4A FERM domain containing 4A
FTO fat mass and obesity associated
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAP GABA(A) receptor-associated protein
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GALR1 galanin receptor 1
GATA4 GATA binding protein 4
GCK glucokinase (hexokinase 4)
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GJA8 gap junction protein, alpha 8, 50kDa
GLB1 galactosidase, beta 1
GLI1 GLI family zinc finger 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRM3 glutamate receptor, metabotropic 3
GRM8 glutamate receptor, metabotropic 8
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
HBB hemoglobin, beta
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIP1 huntingtin interacting protein 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOMER1 homer scaffolding protein 1
HOMER2 homer scaffolding protein 2
HOXD9 homeobox D9
HPSE heparanase
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IL15 interleukin 15
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL5 interleukin 5
INHA inhibin, alpha
INSR insulin receptor
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK2 Janus kinase 2
KAT2B K(lysine) acetyltransferase 2B
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KIAA0040 KIAA0040
KLF11 Kruppel-like factor 11
KLHDC8A kelch domain containing 8A
KPNA3 karyopherin alpha 3 (importin alpha 4)
LGALS1 lectin, galactoside-binding, soluble, 1
LGMN legumain
LMAN2 lectin, mannose-binding 2
LMAN2L lectin, mannose-binding 2-like
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MAOA monoamine oxidase A
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MCFD2 multiple coagulation factor deficiency 2
MCL1 myeloid cell leukemia 1
MDFI MyoD family inhibitor
MECOM MDS1 and EVI1 complex locus
MELK maternal embryonic leucine zipper kinase
MET MET proto-oncogene, receptor tyrosine kinase
MITF microphthalmia-associated transcription factor
MKL1 megakaryoblastic leukemia (translocation) 1
MLH1 mutL homolog 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MMP9 matrix metallopeptidase 9
MPDZ multiple PDZ domain protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCAM1 neural cell adhesion molecule 1
NEUROD2 neuronal differentiation 2
NEXN nexilin (F actin binding protein)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NKAIN1 Na+/K+ transporting ATPase interacting 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPPA natriuretic peptide A
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NPY2R neuropeptide Y receptor Y2
NPY5R neuropeptide Y receptor Y5
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRBF2 nuclear receptor binding factor 2
NRD1 nardilysin (N-arginine dibasic convertase)
NRXN1 neurexin 1
NRXN3 neurexin 3
NSD1 nuclear receptor binding SET domain protein 1
NSF N-ethylmaleimide-sensitive factor
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NTSR1 neurotensin receptor 1 (high affinity)
NUAK1 NUAK family, SNF1-like kinase, 1
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
PARP1 poly (ADP-ribose) polymerase 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PDYN prodynorphin
PER3 period circadian clock 3
PEX5L peroxisomal biogenesis factor 5-like
PHF3 PHD finger protein 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PNMT phenylethanolamine N-methyltransferase
PNOC prepronociceptin
POMC proopiomelanocortin
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCE protein kinase C, epsilon
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PRNP prion protein
PROKR2 prokineticin receptor 2
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAB7A RAB7A, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RB1 retinoblastoma 1
REN renin
RGS17 regulator of G-protein signaling 17
RHOA ras homolog family member A
RICTOR RPTOR independent companion of MTOR, complex 2
ROR1 receptor tyrosine kinase-like orphan receptor 1
S100A4 S100 calcium binding protein A4
SCARB1 scavenger receptor class B, member 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCN4B sodium channel, voltage gated, type IV beta subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SDHAF3 succinate dehydrogenase complex assembly factor 3
SELE selectin E
SERINC2 serine incorporator 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGCE sarcoglycan, epsilon
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1
SH2D1A SH2 domain containing 1A
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHH sonic hedgehog
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SNAI1 snail family zinc finger 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX2 SRY (sex determining region Y)-box 2
SP1 Sp1 transcription factor
SPAST spastin
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STH saitohin
SYPL1 synaptophysin-like 1
TACR1 tachykinin receptor 1
TACR3 tachykinin receptor 3
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAS2R16 taste receptor, type 2, member 16
TAS2R38 taste receptor, type 2, member 38
TBC1D15 TBC1 domain family, member 15
TBX21 T-box 21
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFB1 transforming growth factor, beta 1
THSD7B thrombospondin, type I, domain containing 7B
TLR2 toll-like receptor 2
TNF tumor necrosis factor
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNPO3 transportin 3
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TRB T cell receptor beta locus
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSNAXIP1 translin-associated factor X interacting protein 1
TTC12 tetratricopeptide repeat domain 12
UBAP2 ubiquitin associated protein 2
UNC5D unc-5 homolog D (C. elegans)
VAV1 vav 1 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WLS wntless Wnt ligand secretion mediator
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZNF699 zinc finger protein 699