dephosphorylation Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. (Gene Ontology, GO_0016311)
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Genes

320 genes co-occuring with the biological term dephosphorylation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACP1 acid phosphatase 1, soluble
ACTN4 actinin, alpha 4
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALPI alkaline phosphatase, intestinal
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APP amyloid beta (A4) precursor protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AR androgen receptor
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARRB1 arrestin, beta 1
ATM ATM serine/threonine kinase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATXN1 ataxin 1
AURKA aurora kinase A
AURKB aurora kinase B
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BANF1 barrier to autointegration factor 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BRSK1 BR serine/threonine kinase 1
BRSK2 BR serine/threonine kinase 2
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CAPN1 calpain 1, (mu/I) large subunit
CARD11 caspase recruitment domain family, member 11
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC6 coiled-coil domain containing 6
CCNA2 cyclin A2
CD36 CD36 molecule (thrombospondin receptor)
CD47 CD47 molecule
CDC14A cell division cycle 14A
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC37 cell division cycle 37
CDCA2 cell division cycle associated 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDK11B cyclin-dependent kinase 11B
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK6 cyclin-dependent kinase 6
CDKN3 cyclin-dependent kinase inhibitor 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CLDN1 claudin 1
CLTC clathrin, heavy chain (Hc)
CNR1 cannabinoid receptor 1 (brain)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CREM cAMP responsive element modulator
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSK c-src tyrosine kinase
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTTN cortactin
CUX1 cut-like homeobox 1
CXCL12 chemokine (C-X-C motif) ligand 12
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAPK1 death-associated protein kinase 1
DAPK3 death-associated protein kinase 3
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DNM1L dynamin 1-like
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
EEF2 eukaryotic translation elongation factor 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF4E eukaryotic translation initiation factor 4E
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENSA endosulfine alpha
EPHA2 EPH receptor A2
EPHB1 EPH receptor B1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
F2R coagulation factor II (thrombin) receptor
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCP1 F-cell production 1
FOXM1 forkhead box M1
FOXP3 forkhead box P3
FPR2 formyl peptide receptor 2
GAK cyclin G associated kinase
GJA1 gap junction protein, alpha 1, 43kDa
GPHN gephyrin
GRB14 growth factor receptor-bound protein 14
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
GYS1 glycogen synthase 1 (muscle)
H2AFX H2A histone family, member X
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC9 histone deacetylase 9
HDGF hepatoma-derived growth factor
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HIST3H3 histone cluster 3, H3
HRAS Harvey rat sarcoma viral oncogene homolog
HSF2 heat shock transcription factor 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL2 interleukin 2
IL21R interleukin 21 receptor
IL4R interleukin 4 receptor
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
INCENP inner centromere protein antigens 135/155kDa
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INPPL1 inositol polyphosphate phosphatase-like 1
INS insulin
IRF3 interferon regulatory factor 3
IRS1 insulin receptor substrate 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
JUN jun proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDR kinase insert domain receptor
KRT8 keratin 8, type II
LACRT lacritin
LEMD3 LEM domain containing 3
LIMK1 LIM domain kinase 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MASTL microtubule associated serine/threonine kinase-like
MCL1 myeloid cell leukemia 1
MET MET proto-oncogene, receptor tyrosine kinase
MINPP1 multiple inositol-polyphosphate phosphatase 1
MKI67 marker of proliferation Ki-67
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLXIPL MLX interacting protein-like
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYH9 myosin, heavy chain 9, non-muscle
NCKIPSD NCK interacting protein with SH3 domain
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFE2L2 nuclear factor, erythroid 2-like 2
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOTCH1 notch 1
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRG1 neuregulin 1
OCLN occludin
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PEA15 phosphoprotein enriched in astrocytes 15
PGAM5 phosphoglycerate mutase family member 5
PHPT1 phosphohistidine phosphatase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKP3 plakophilin 3
PLAUR plasminogen activator, urokinase receptor
PLK1 polo-like kinase 1
PLXNB1 plexin B1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPA1 pyrophosphatase (inorganic) 1
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP4C protein phosphatase 4, catalytic subunit
PPP5C protein phosphatase 5, catalytic subunit
PPP6C protein phosphatase 6, catalytic subunit
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PTEN phosphatase and tensin homolog
PTH parathyroid hormone
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRJ protein tyrosine phosphatase, receptor type, J
PXN paxillin
RAB11A RAB11A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD51 RAD51 recombinase
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RB1 retinoblastoma 1
RBM17 RNA binding motif protein 17
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RMDN3 regulator of microtubule dynamics 3
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPA2 replication protein A2, 32kDa
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUVBL1 RuvB-like AAA ATPase 1
S100A1 S100 calcium binding protein A1
SAFB scaffold attachment factor B
SDC1 syndecan 1
SDCBP syndecan binding protein (syntenin)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLBP stem-loop binding protein
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SP1 Sp1 transcription factor
SPRED1 sprouty-related, EVH1 domain containing 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSH1 slingshot protein phosphatase 1
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK11 serine/threonine kinase 11
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
SYK spleen tyrosine kinase
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TEAD4 TEA domain family member 4
TEC tec protein tyrosine kinase
TGFB1 transforming growth factor, beta 1
THRA thyroid hormone receptor, alpha
TIMP1 TIMP metallopeptidase inhibitor 1
TJP1 tight junction protein 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TRIM28 tripartite motif containing 28
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TXNIP thioredoxin interacting protein
U2AF2 U2 small nuclear RNA auxiliary factor 2
UNC5B unc-5 homolog B (C. elegans)
VASP vasodilator-stimulated phosphoprotein
VAV1 vav 1 guanine nucleotide exchange factor
VCL vinculin
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
WASF1 WAS protein family, member 1
WEE1 WEE1 G2 checkpoint kinase
WWTR1 WW domain containing transcription regulator 1
YAP1 Yes-associated protein 1
YY1AP1 YY1 associated protein 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa