depressive Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

225 genes co-occuring with the biological term depressive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACE angiotensin I converting enzyme
ADCY3 adenylate cyclase 3
ADCY7 adenylate cyclase 7
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA2A adrenoceptor alpha 2A
ADRA2C adrenoceptor alpha 2C
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
ADRBK1 adrenergic, beta, receptor kinase 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARTN artemin
ASMT acetylserotonin O-methyltransferase
AVP arginine vasopressin
AVPR1A arginine vasopressin receptor 1A
BCL9 B-cell CLL/lymphoma 9
BDNF brain-derived neurotrophic factor
BICC1 BicC family RNA binding protein 1
C9ORF72 chromosome 9 open reading frame 72
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CC2D1A coiled-coil and C2 domain containing 1A
CCBL2 cysteine conjugate-beta lyase 2
CDCA7L cell division cycle associated 7-like
CDH7 cadherin 7, type 2
CFH complement factor H
CHRM2 cholinergic receptor, muscarinic 2
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CREM cAMP responsive element modulator
CRHBP corticotropin releasing hormone binding protein
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRP C-reactive protein, pentraxin-related
CRY1 cryptochrome circadian clock 1
CRY2 cryptochrome circadian clock 2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNND2 catenin (cadherin-associated protein), delta 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DAO D-amino-acid oxidase
DAOA D-amino acid oxidase activator
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCANP1 dendritic cell-associated nuclear protein
DDIT4 DNA-damage-inducible transcript 4
DEL22Q11.2 Chromosome 22q11.2 deletion syndrome, distal
DISC1 disrupted in schizophrenia 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DUSP1 dual specificity phosphatase 1
EGF epidermal growth factor
EHD3 EH-domain containing 3
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
FAAH fatty acid amide hydrolase
FASN fatty acid synthase
FGFR1 fibroblast growth factor receptor 1
FKBP4 FK506 binding protein 4, 59kDa
FKBP5 FK506 binding protein 5
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FREM3 FRAS1 related extracellular matrix 3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAL galanin/GMAP prepropeptide
GCH1 GTP cyclohydrolase 1
GDNF glial cell derived neurotrophic factor
GFAP glial fibrillary acidic protein
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GMIP GEM interacting protein
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPR50 G protein-coupled receptor 50
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GRM7 glutamate receptor, metabotropic 7
GSK3B glycogen synthase kinase 3 beta
GSR glutathione reductase
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HSPA4 heat shock 70kDa protein 4
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFN1@ interferon, type 1, cluster
IFNA2 interferon, alpha 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL11 interleukin 11
IL18 interleukin 18
IL1B interleukin 1, beta
IL6 interleukin 6
IL7 interleukin 7
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LEP leptin
LEPQTL1 Leptin, serum levels of
LGSN lengsin, lens protein with glutamine synthetase domain
LMX1B LIM homeobox transcription factor 1, beta
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LTBP1 latent transforming growth factor beta binding protein 1
MAOA monoamine oxidase A
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP10 matrix metallopeptidase 10
MPO myeloperoxidase
MT-TK tRNA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTNR1B melatonin receptor 1B
MYT1L myelin transcription factor 1-like
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NGFR nerve growth factor receptor
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPSR1 neuropeptide S receptor 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRG1 neuregulin 1
NTF3 neurotrophin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OGG1 8-oxoguanine DNA glycosylase
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAWR PRKC, apoptosis, WT1, regulator
PCDH17 protocadherin 17
PCLO piccolo presynaptic cytomatrix protein
PCNT pericentrin
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM5 PDZ and LIM domain 5
PDYN prodynorphin
PER3 period circadian clock 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKCG protein kinase C, gamma
PRL prolactin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRR protein tyrosine phosphatase, receptor type, R
PWAR4 Prader Willi/Angelman region RNA 4
REEP5 receptor accessory protein 5
REN renin
REST RE1-silencing transcription factor
RGS1 regulator of G-protein signaling 1
RGS4 regulator of G-protein signaling 4
RORA RAR-related orphan receptor A
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A10 S100 calcium binding protein A10
S100B S100 calcium binding protein B
SAT1 spermidine/spermine N1-acetyltransferase 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRT1 sirtuin 1
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLIT3 slit homolog 3 (Drosophila)
SNAP25 synaptosomal-associated protein, 25kDa
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SPI1 Spi-1 proto-oncogene
SST somatostatin
TAAR6 trace amine associated receptor 6
TACR1 tachykinin receptor 1
TACR2 tachykinin receptor 2
TEF thyrotrophic embryonic factor
TH tyrosine hydroxylase
TNF tumor necrosis factor
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TREM1 triggering receptor expressed on myeloid cells 1
TSNAX translin-associated factor X
TTR transthyretin
TYROBP TYRO protein tyrosine kinase binding protein
USP46 ubiquitin specific peptidase 46
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WWC1 WW and C2 domain containing 1
XBP1 X-box binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZBTB20 zinc finger and BTB domain containing 20