| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the deptropine-6523 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| AK2 | adenylate kinase 2 |
| ALS2CL | ALS2 C-terminal like |
| ASPH | aspartate beta-hydroxylase |
| BBS9 | Bardet-Biedl syndrome 9 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BGN | biglycan |
| BTG2 | BTG family, member 2 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CALD1 | caldesmon 1 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC71 | coiled-coil domain containing 71 |
| CD6 | CD6 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDC25A | cell division cycle 25A |
| CLTA | clathrin, light chain A |
| CNN3 | calponin 3, acidic |
| CNTNAP2 | contactin associated protein-like 2 |
| CORO2B | coronin, actin binding protein, 2B |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CST1 | cystatin SN |
| DICER1 | dicer 1, ribonuclease type III |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DTNA | dystrobrevin, alpha |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ETV5 | ets variant 5 |
| FAM129A | family with sequence similarity 129, member A |
| FBLN1 | fibulin 1 |
| FBN1 | fibrillin 1 |
| FGB | fibrinogen beta chain |
| FLJ11292 | |
| FOXA2 | forkhead box A2 |
| FSCN1 | fascin actin-bundling protein 1 |
| FYB | FYN binding protein |
| GAP43 | growth associated protein 43 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPR135 | G protein-coupled receptor 135 |
| GPR182 | G protein-coupled receptor 182 |
| GPR85 | G protein-coupled receptor 85 |
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 |
| GYPB | glycophorin B (MNS blood group) |
| HBB | hemoglobin, beta |
| HBEGF | heparin-binding EGF-like growth factor |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HDAC5 | histone deacetylase 5 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HYAL4 | hyaluronoglucosaminidase 4 |
| ICAM1 | intercellular adhesion molecule 1 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL1RN | interleukin 1 receptor antagonist |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLK7 | kallikrein-related peptidase 7 |
| KNG1 | kininogen 1 |
| LRRC40 | leucine rich repeat containing 40 |
| MSI1 | musashi RNA-binding protein 1 |
| MTSS1 | metastasis suppressor 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NID1 | nidogen 1 |
| NUDCD3 | NudC domain containing 3 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDGFC | platelet derived growth factor C |
| PEX5 | peroxisomal biogenesis factor 5 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLXNC1 | plexin C1 |
| POU2F2 | POU class 2 homeobox 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTAFR | platelet-activating factor receptor |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS20 | regulator of G-protein signaling 20 |
| RUNX1 | runt-related transcription factor 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SFTPD | surfactant protein D |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| TFCP2 | transcription factor CP2 |
| TRD | T cell receptor delta locus |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TRIM3 | tripartite motif containing 3 |
| TTC38 | tetratricopeptide repeat domain 38 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF222 | zinc finger protein 222 |
| ZNF384 | zinc finger protein 384 |
| ZNF407 | zinc finger protein 407 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| AZI2 | 5-azacytidine induced 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BMP15 | bone morphogenetic protein 15 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C5 | complement component 5 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCDC132 | coiled-coil domain containing 132 |
| CHEK2 | checkpoint kinase 2 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CPOX | coproporphyrinogen oxidase |
| CTAGE9 | CTAGE family, member 9 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| F8 | coagulation factor VIII, procoagulant component |
| FAM155B | family with sequence similarity 155, member B |
| FANCC | Fanconi anemia, complementation group C |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GID4 | GID complex subunit 4 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HOXA4 | homeobox A4 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT54 | intraflagellar transport 54 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL4R | interleukin 4 receptor |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| KIAA0556 | KIAA0556 |
| KLHL25 | kelch-like family member 25 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMBR1L | limb development membrane protein 1-like |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYRM9 | LYR motif containing 9 |
| MANBA | mannosidase, beta A, lysosomal |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTCL1 | microtubule crosslinking factor 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NOL12 | nucleolar protein 12 |
| NRBF2 | nuclear receptor binding factor 2 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| NUPL2 | nucleoporin like 2 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PCDHB3 | protocadherin beta 3 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PER3 | period circadian clock 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRR15L | proline rich 15-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB23 | RAB23, member RAS oncogene family |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF25 | ring finger protein 25 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPL10L | ribosomal protein L10-like |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SECTM1 | secreted and transmembrane 1 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPIDR | scaffolding protein involved in DNA repair |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYBU | syntabulin (syntaxin-interacting) |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TSPAN2 | tetraspanin 2 |
| TTBK2 | tau tubulin kinase 2 |
| UBXN8 | UBX domain protein 8 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZNF10 | zinc finger protein 10 |
| ZNF280D | zinc finger protein 280D |
| ZNF492 | zinc finger protein 492 |
| ZNF573 | zinc finger protein 573 |
| ZNF675 | zinc finger protein 675 |
| ZNF701 | zinc finger protein 701 |