depudecin-874 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the depudecin-874 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ADRA1D adrenoceptor alpha 1D
AFAP1 actin filament associated protein 1
ANK2 ankyrin 2, neuronal
AREG amphiregulin
ARMC6 armadillo repeat containing 6
ATXN3 ataxin 3
C7ORF69 chromosome 7 open reading frame 69
CALD1 caldesmon 1
CARD9 caspase recruitment domain family, member 9
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASZ1 castor zinc finger 1
CBR3 carbonyl reductase 3
CCDC69 coiled-coil domain containing 69
CD68 CD68 molecule
CDC14B cell division cycle 14B
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLDN1 claudin 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL9A3 collagen, type IX, alpha 3
CSHL1 chorionic somatomammotropin hormone-like 1
CTTN cortactin
CXCL8 chemokine (C-X-C motif) ligand 8
CXORF21 chromosome X open reading frame 21
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DSCAM Down syndrome cell adhesion molecule
DSPP dentin sialophosphoprotein
EBF2 early B-cell factor 2
EFNA3 ephrin-A3
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EPHX2 epoxide hydrolase 2, cytoplasmic
FILIP1L filamin A interacting protein 1-like
FLJ11292
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GK glycerol kinase
GPC1 glypican 1
HAMP hepcidin antimicrobial peptide
HLA-E major histocompatibility complex, class I, E
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
ICAM1 intercellular adhesion molecule 1
IL1R2 interleukin 1 receptor, type II
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCTD7 potassium channel tetramerization domain containing 7
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLF9 Kruppel-like factor 9
KLHL24 kelch-like family member 24
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LIG4 ligase IV, DNA, ATP-dependent
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRC40 leucine rich repeat containing 40
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBNL3 muscleblind-like splicing regulator 3
METTL7A methyltransferase like 7A
MFAP3L microfibrillar-associated protein 3-like
MT1E metallothionein 1E
MYCNOS MYCN opposite strand
MYT1L myelin transcription factor 1-like
NLGN1 neuroligin 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NT5M 5',3'-nucleotidase, mitochondrial
NUP88 nucleoporin 88kDa
OGFR opioid growth factor receptor
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKD2L2 polycystic kidney disease 2-like 2
PPARG peroxisome proliferator-activated receptor gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTHLH parathyroid hormone-like hormone
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRF protein tyrosine phosphatase, receptor type, F
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RECQL5 RecQ protein-like 5
RFPL1 ret finger protein-like 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUFY3 RUN and FYVE domain containing 3
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRAL2 SIR2 antiphage like 2
SLC12A8 solute carrier family 12, member 8
SOCS2 suppressor of cytokine signaling 2
SORBS2 sorbin and SH3 domain containing 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEX261 testis expressed 261
TMC5 transmembrane channel-like 5
TRAK1 trafficking protein, kinesin binding 1
TRIM10 tripartite motif containing 10
USP34 ubiquitin specific peptidase 34
VGF VGF nerve growth factor inducible
VIPR2 vasoactive intestinal peptide receptor 2

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACVR2B activin A receptor, type IIB
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGAP11A Rho GTPase activating protein 11A
ATP7B ATPase, Cu++ transporting, beta polypeptide
BANP BTG3 associated nuclear protein
BCL2L2 BCL2-like 2
BTBD2 BTB (POZ) domain containing 2
C1ORF56 chromosome 1 open reading frame 56
C5ORF45 chromosome 5 open reading frame 45
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMKMT calmodulin-lysine N-methyltransferase
CASD1 CAS1 domain containing 1
CBX8 chromobox homolog 8
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CLK4 CDC-like kinase 4
COPS7B COP9 signalosome subunit 7B
CRABP1 cellular retinoic acid binding protein 1
CRTAP cartilage associated protein
DMTF1 cyclin D binding myb-like transcription factor 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
FRS2 fibroblast growth factor receptor substrate 2
GAN gigaxonin
GDAP2 ganglioside induced differentiation associated protein 2
GLTP glycolipid transfer protein
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMEB1 glucocorticoid modulatory element binding protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
ING3 inhibitor of growth family, member 3
JMJD1C jumonji domain containing 1C
KATNBL1 katanin p80 subunit B-like 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0894 KIAA0894 protein
KPTN kaptin (actin binding protein)
LIN7A lin-7 homolog A (C. elegans)
LOC730101 uncharacterized LOC730101
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MCMBP minichromosome maintenance complex binding protein
MIS18BP1 MIS18 binding protein 1
MRPL44 mitochondrial ribosomal protein L44
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NHEJ1 nonhomologous end-joining factor 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCYOX1 prenylcysteine oxidase 1
PGPEP1 pyroglutamyl-peptidase I
PISD phosphatidylserine decarboxylase
PROCR protein C receptor, endothelial
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS22 protease, serine, 22
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RANBP17 RAN binding protein 17
REPS2 RALBP1 associated Eps domain containing 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SDC3 syndecan 3
SECISBP2 SECIS binding protein 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNHG3 small nucleolar RNA host gene 3
SPAG1 sperm associated antigen 1
SPIDR scaffolding protein involved in DNA repair
SPON2 spondin 2, extracellular matrix protein
SREK1IP1 SREK1-interacting protein 1
SSFA2 sperm specific antigen 2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TH tyrosine hydroxylase
TMEM62 transmembrane protein 62
TMPRSS3 transmembrane protease, serine 3
TRIM16 tripartite motif containing 16
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
USP6NL USP6 N-terminal like
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WDR76 WD repeat domain 76
XKR8 XK, Kell blood group complex subunit-related family, member 8
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB22 zinc finger and BTB domain containing 22
ZBTB39 zinc finger and BTB domain containing 39
ZBTB48 zinc finger and BTB domain containing 48
ZNF276 zinc finger protein 276
ZNF280D zinc finger protein 280D
ZNF33B zinc finger protein 33B
ZNF430 zinc finger protein 430
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675
ZNF692 zinc finger protein 692
ZNF7 zinc finger protein 7