| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the depudecin-982 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ABHD6 | abhydrolase domain containing 6 |
| ACOT8 | acyl-CoA thioesterase 8 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDC25A | cell division cycle 25A |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTH | cystathionine gamma-lyase |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DESI2 | desumoylating isopeptidase 2 |
| DIXDC1 | DIX domain containing 1 |
| DMC1 | DNA meiotic recombinase 1 |
| DUSP6 | dual specificity phosphatase 6 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPOR | erythropoietin receptor |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FOXO1 | forkhead box O1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GAMT | guanidinoacetate N-methyltransferase |
| GLB1L | galactosidase, beta 1-like |
| GLRX | glutaredoxin (thioltransferase) |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HFE | hemochromatosis |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HOXB7 | homeobox B7 |
| IGF1R | insulin-like growth factor 1 receptor |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IRF1 | interferon regulatory factor 1 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KIAA0895 | KIAA0895 |
| KLHL23 | kelch-like family member 23 |
| KLHL24 | kelch-like family member 24 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LRRC40 | leucine rich repeat containing 40 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPT | microtubule-associated protein tau |
| MED6 | mediator complex subunit 6 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MFAP3 | microfibrillar-associated protein 3 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MTM1 | myotubularin 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NAIP | NLR family, apoptosis inhibitory protein |
| NF2 | neurofibromin 2 (merlin) |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OGFR | opioid growth factor receptor |
| PHF14 | PHD finger protein 14 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLH | polymerase (DNA directed), eta |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PVR | poliovirus receptor |
| RAB26 | RAB26, member RAS oncogene family |
| RHOQ | ras homolog family member Q |
| RNFT1 | ring finger protein, transmembrane 1 |
| RNFT2 | ring finger protein, transmembrane 2 |
| S100A8 | S100 calcium binding protein A8 |
| SCRN3 | secernin 3 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMAD3 | SMAD family member 3 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| STRN | striatin, calmodulin binding protein |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TDRKH | tudor and KH domain containing |
| TEAD3 | TEA domain family member 3 |
| TMEM63A | transmembrane protein 63A |
| TTC33 | tetratricopeptide repeat domain 33 |
| TXNIP | thioredoxin interacting protein |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF365 | zinc finger protein 365 |
| ZNF571 | zinc finger protein 571 |
| ZNF76 | zinc finger protein 76 |
| ZNF816 | zinc finger protein 816 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AFF4 | AF4/FMR2 family, member 4 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BRD9 | bromodomain containing 9 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC94 | coiled-coil domain containing 94 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CLK4 | CDC-like kinase 4 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP8 | dual specificity phosphatase 8 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| FAAH | fatty acid amide hydrolase |
| FAM193B | family with sequence similarity 193, member B |
| FBXL12 | F-box and leucine-rich repeat protein 12 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| HAUS7 | HAUS augmin-like complex, subunit 7 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 |
| HIRA | histone cell cycle regulator |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4C | histone cluster 1, H4c |
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase |
| HMHA1 | histocompatibility (minor) HA-1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| KRT13 | keratin 13, type I |
| LINS | lines homolog (Drosophila) |
| LMNB1 | lamin B1 |
| LYRM9 | LYR motif containing 9 |
| METTL2B | methyltransferase like 2B |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXD3 | MAX dimerization protein 3 |
| MYO19 | myosin XIX |
| NAV2 | neuron navigator 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PARPBP | PARP1 binding protein |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PSKH1 | protein serine kinase H1 |
| RANBP17 | RAN binding protein 17 |
| RARS | arginyl-tRNA synthetase |
| RPS21 | ribosomal protein S21 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SEC61B | Sec61 beta subunit |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F |
| SRSF4 | serine/arginine-rich splicing factor 4 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TBC1D12 | TBC1 domain family, member 12 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TMEM110 | transmembrane protein 110 |
| TMEM185B | transmembrane protein 185B |
| TNRC6B | trinucleotide repeat containing 6B |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| ULBP2 | UL16 binding protein 2 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP21 | ubiquitin specific peptidase 21 |
| VASP | vasodilator-stimulated phosphoprotein |
| VGF | VGF nerve growth factor inducible |
| WDR60 | WD repeat domain 60 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZNF141 | zinc finger protein 141 |
| ZNF35 | zinc finger protein 35 |
| ZNF665 | zinc finger protein 665 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |