dequalinium chloride-6296 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the dequalinium chloride-6296 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADAM22 ADAM metallopeptidase domain 22
AFF1 AF4/FMR2 family, member 1
AIM1L absent in melanoma 1-like
AKR1C1 aldo-keto reductase family 1, member C1
ALDOB aldolase B, fructose-bisphosphate
ASB1 ankyrin repeat and SOCS box containing 1
ASTN1 astrotactin 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C8ORF44 chromosome 8 open reading frame 44
CABIN1 calcineurin binding protein 1
CALD1 caldesmon 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCNO cyclin O
CCPG1 cell cycle progression 1
CD68 CD68 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDHR2 cadherin-related family member 2
CDK13 cyclin-dependent kinase 13
CEP164 centrosomal protein 164kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIC capicua transcriptional repressor
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DENND3 DENN/MADD domain containing 3
DLC1 DLC1 Rho GTPase activating protein
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EMID1 EMI domain containing 1
EML3 echinoderm microtubule associated protein like 3
EPHB2 EPH receptor B2
ESRRG estrogen-related receptor gamma
FAM118A family with sequence similarity 118, member A
FBXO21 F-box protein 21
FLT1 fms-related tyrosine kinase 1
FXYD2 FXYD domain containing ion transport regulator 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GATA2 GATA binding protein 2
GGT1 gamma-glutamyltransferase 1
GPC3 glypican 3
GRAMD1C GRAM domain containing 1C
HOMER3 homer scaffolding protein 3
HOXC11 homeobox C11
IGL immunoglobulin lambda locus
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INO80D INO80 complex subunit D
IRF4 interferon regulatory factor 4
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM4B lysine (K)-specific demethylase 4B
KIF1A kinesin family member 1A
KLK7 kallikrein-related peptidase 7
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LY6D lymphocyte antigen 6 complex, locus D
MFGE8 milk fat globule-EGF factor 8 protein
MTRF1L mitochondrial translational release factor 1-like
NOD1 nucleotide-binding oligomerization domain containing 1
NOL12 nucleolar protein 12
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPEPL1 aminopeptidase-like 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTM neurotrimin
NTS neurotensin
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLAG1 pleiomorphic adenoma gene 1
PPARD peroxisome proliferator-activated receptor delta
PTCH1 patched 1
PTRF polymerase I and transcript release factor
RAB3B RAB3B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
REC8 REC8 meiotic recombination protein
RGS10 regulator of G-protein signaling 10
RIN3 Ras and Rab interactor 3
RNF19B ring finger protein 19B
SCARA3 scavenger receptor class A, member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SPRR1A small proline-rich protein 1A
SSH3 slingshot protein phosphatase 3
SSX1 synovial sarcoma, X breakpoint 1
STC2 stanniocalcin 2
SYCP2 synaptonemal complex protein 2
TBL1Y transducin (beta)-like 1, Y-linked
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAV8-3 T cell receptor alpha variable 8-3
TRIB3 tribbles pseudokinase 3
TRIM29 tripartite motif containing 29
WDR25 WD repeat domain 25
WDR78 WD repeat domain 78
WSB1 WD repeat and SOCS box containing 1
ZFP30 ZFP30 zinc finger protein
ZNF276 zinc finger protein 276
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ADAM15 ADAM metallopeptidase domain 15
ADGRF1 adhesion G protein-coupled receptor F1
ANAPC2 anaphase promoting complex subunit 2
ASB13 ankyrin repeat and SOCS box containing 13
ASL argininosuccinate lyase
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BCL9 B-cell CLL/lymphoma 9
BIK BCL2-interacting killer (apoptosis-inducing)
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF73 chromosome 11 open reading frame 73
C1ORF106 chromosome 1 open reading frame 106
C1ORF112 chromosome 1 open reading frame 112
C1ORF56 chromosome 1 open reading frame 56
CCNT1 cyclin T1
CHEK2 checkpoint kinase 2
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST10 carbohydrate sulfotransferase 10
CINP cyclin-dependent kinase 2 interacting protein
CLIP4 CAP-GLY domain containing linker protein family, member 4
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CST6 cystatin E/M
CXORF56 chromosome X open reading frame 56
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEAF1 DEAF1 transcription factor
DNA2 DNA replication helicase/nuclease 2
DNAAF2 dynein, axonemal, assembly factor 2
EHD3 EH-domain containing 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FSD1 fibronectin type III and SPRY domain containing 1
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HCFC2 host cell factor C2
HPS6 Hermansky-Pudlak syndrome 6
HYI hydroxypyruvate isomerase (putative)
IFNAR1 interferon (alpha, beta and omega) receptor 1
IREB2 iron-responsive element binding protein 2
KDM1A lysine (K)-specific demethylase 1A
KIFC1 kinesin family member C1
LYPLA2P1 lysophospholipase II pseudogene 1
LZTR1 leucine-zipper-like transcription regulator 1
MFSD11 major facilitator superfamily domain containing 11
MNX1 motor neuron and pancreas homeobox 1
MRPL28 mitochondrial ribosomal protein L28
MTG1 mitochondrial ribosome-associated GTPase 1
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUC3B mucin 3B, cell surface associated
MUM1 melanoma associated antigen (mutated) 1
NID2 nidogen 2 (osteonidogen)
NPM3 nucleophosmin/nucleoplasmin 3
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PCSK7 proprotein convertase subtilisin/kexin type 7
PEMT phosphatidylethanolamine N-methyltransferase
PER3 period circadian clock 3
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRMT7 protein arginine methyltransferase 7
PRR14L proline rich 14-like
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RARS arginyl-tRNA synthetase
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SLTM SAFB-like, transcription modulator
STARD13 StAR-related lipid transfer (START) domain containing 13
SYNC syncoilin, intermediate filament protein
SYTL2 synaptotagmin-like 2
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D10B TBC1 domain family, member 10B
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TMEM132A transmembrane protein 132A
TMEM159 transmembrane protein 159
TMEM62 transmembrane protein 62
TOR4A torsin family 4, member A
TPCN1 two pore segment channel 1
TRAIP TRAF interacting protein
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
USP39 ubiquitin specific peptidase 39
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR18 WD repeat domain 18
XYLT2 xylosyltransferase II
YIPF5 Yip1 domain family, member 5
ZBTB10 zinc finger and BTB domain containing 10
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF197 zinc finger protein 197
ZNF239 zinc finger protein 239
ZNF304 zinc finger protein 304
ZNF324 zinc finger protein 324
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675
ZSCAN5A zinc finger and SCAN domain containing 5A