| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the desipramine-5292 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACLY | ATP citrate lyase |
| APP | amyloid beta (A4) precursor protein |
| AQP3 | aquaporin 3 (Gill blood group) |
| AREG | amphiregulin |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ARMCX3 | armadillo repeat containing, X-linked 3 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ASPH | aspartate beta-hydroxylase |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| ATXN1 | ataxin 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BMP1 | bone morphogenetic protein 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CBR3 | carbonyl reductase 3 |
| CCNG2 | cyclin G2 |
| CHKA | choline kinase alpha |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDND1 | claudin domain containing 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CYHR1 | cysteine/histidine-rich 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHCR7 | 7-dehydrocholesterol reductase |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DUSP4 | dual specificity phosphatase 4 |
| EHD3 | EH-domain containing 3 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| FBXO22 | F-box protein 22 |
| FCF1 | FCF1 rRNA-processing protein |
| FOXD1 | forkhead box D1 |
| FZD7 | frizzled class receptor 7 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GRAMD3 | GRAM domain containing 3 |
| GTF2I | general transcription factor IIi |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HOXC11 | homeobox C11 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| INSIG1 | insulin induced gene 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KITLG | KIT ligand |
| KLF9 | Kruppel-like factor 9 |
| LAMB3 | laminin, beta 3 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIF | leukemia inhibitory factor |
| LPIN1 | lipin 1 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LYST | lysosomal trafficking regulator |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MSMO1 | methylsterol monooxygenase 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MVK | mevalonate kinase |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PGM3 | phosphoglucomutase 3 |
| PLA2G3 | phospholipase A2, group III |
| PLAUR | plasminogen activator, urokinase receptor |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| POLR3C | polymerase (RNA) III (DNA directed) polypeptide C (62kD) |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCHIP1 | schwannomin interacting protein 1 |
| SEC24D | SEC24 family member D |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SQLE | squalene epoxidase |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STX5 | syntaxin 5 |
| TRIM2 | tripartite motif containing 2 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP13A2 | ATPase type 13A2 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| AXIN1 | axin 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CHMP6 | charged multivesicular body protein 6 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CORO2A | coronin, actin binding protein, 2A |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EVPL | envoplakin |
| FAM169A | family with sequence similarity 169, member A |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FAR2 | fatty acyl CoA reductase 2 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FGGY | FGGY carbohydrate kinase domain containing |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HCFC2 | host cell factor C2 |
| HELLS | helicase, lymphoid-specific |
| HIST1H1E | histone cluster 1, H1e |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IL15RA | interleukin 15 receptor, alpha |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| IPP | intracisternal A particle-promoted polypeptide |
| IRF9 | interferon regulatory factor 9 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LARS | leucyl-tRNA synthetase |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LINS | lines homolog (Drosophila) |
| LOC100287590 | uncharacterized LOC100287590 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MEIS1 | Meis homeobox 1 |
| METTL16 | methyltransferase like 16 |
| METTL2B | methyltransferase like 2B |
| METTL8 | methyltransferase like 8 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGA | MGA, MAX dimerization protein |
| NAT10 | N-acetyltransferase 10 (GCN5-related) |
| NPY1R | neuropeptide Y receptor Y1 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PCYOX1L | prenylcysteine oxidase 1 like |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKCZ | protein kinase C, zeta |
| PRMT7 | protein arginine methyltransferase 7 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
| RFTN1 | raftlin, lipid raft linker 1 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| SCAI | suppressor of cancer cell invasion |
| SIK1 | salt-inducible kinase 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| TBC1D16 | TBC1 domain family, member 16 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMC7 | transmembrane channel-like 7 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TUBA3C | tubulin, alpha 3c |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR46 | WD repeat domain 46 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF239 | zinc finger protein 239 |
| ZNF586 | zinc finger protein 586 |
| ZNF611 | zinc finger protein 611 |
| ZNF639 | zinc finger protein 639 |
| ZNF652 | zinc finger protein 652 |
| ZNF669 | zinc finger protein 669 |
