| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the desipramine-6693 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AARS | alanyl-tRNA synthetase |
| ADAP1 | ArfGAP with dual PH domains 1 |
| ADGB | androglobin |
| ALDOB | aldolase B, fructose-bisphosphate |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| CABP2 | calcium binding protein 2 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCNO | cyclin O |
| CDC14A | cell division cycle 14A |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSPG4 | chondroitin sulfate proteoglycan 4 |
| CTH | cystathionine gamma-lyase |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CXXC4 | CXXC finger protein 4 |
| DCLK2 | doublecortin-like kinase 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DENND3 | DENN/MADD domain containing 3 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP5 | dual specificity phosphatase 5 |
| EFNA3 | ephrin-A3 |
| ESR2 | estrogen receptor 2 (ER beta) |
| EXO5 | exonuclease 5 |
| GAN | gigaxonin |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GK3P | glycerol kinase 3 pseudogene |
| GLI2 | GLI family zinc finger 2 |
| GPR1 | G protein-coupled receptor 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| ICOS | inducible T-cell co-stimulator |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INSIG1 | insulin induced gene 1 |
| IQCK | IQ motif containing K |
| JUND | jun D proto-oncogene |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA1467 | KIAA1467 |
| KLF4 | Kruppel-like factor 4 (gut) |
| LIG3 | ligase III, DNA, ATP-dependent |
| LIPG | lipase, endothelial |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MDM4 | MDM4, p53 regulator |
| MFAP3L | microfibrillar-associated protein 3-like |
| MMP13 | matrix metallopeptidase 13 |
| MSX2 | msh homeobox 2 |
| MX1 | MX dynamin-like GTPase 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PARK2 | parkin RBR E3 ubiquitin protein ligase |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRDM10 | PR domain containing 10 |
| PRKCE | protein kinase C, epsilon |
| PVR | poliovirus receptor |
| QKI | QKI, KH domain containing, RNA binding |
| RAB6A | RAB6A, member RAS oncogene family |
| RARG | retinoic acid receptor, gamma |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUNX1 | runt-related transcription factor 1 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCARB2 | scavenger receptor class B, member 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPTB | spectrin, beta, erythrocytic |
| SRRT | serrate, RNA effector molecule |
| STK3 | serine/threonine kinase 3 |
| SYT1 | synaptotagmin I |
| TGFB2 | transforming growth factor, beta 2 |
| TLX2 | T-cell leukemia homeobox 2 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM3 | tripartite motif containing 3 |
| UPK3B | uroplakin 3B |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZNF500 | zinc finger protein 500 |
| ZNF518A | zinc finger protein 518A |
| ZNF589 | zinc finger protein 589 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| AEN | apoptosis enhancing nuclease |
| ANOS1 | anosmin 1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| AXIN1 | axin 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BMP15 | bone morphogenetic protein 15 |
| BTC | betacellulin |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CBX8 | chromobox homolog 8 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDH7 | cadherin 7, type 2 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CLDN8 | claudin 8 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CYB5R2 | cytochrome b5 reductase 2 |
| DCLRE1B | DNA cross-link repair 1B |
| DDN | dendrin |
| DENND5B | DENN/MADD domain containing 5B |
| E2F8 | E2F transcription factor 8 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ENDOG | endonuclease G |
| ETNK2 | ethanolamine kinase 2 |
| FAM53B | family with sequence similarity 53, member B |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GALK1 | galactokinase 1 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3I | histone cluster 1, H3i |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA7 | homeobox A7 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIRREL | kin of IRRE like (Drosophila) |
| KRT75 | keratin 75, type II |
| KRT9 | keratin 9, type I |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC257152 | uncharacterized LOC257152 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MMP9 | matrix metallopeptidase 9 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MUC3A | mucin 3A, cell surface associated |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NABP1 | nucleic acid binding protein 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRTN | neurturin |
| ORC1 | origin recognition complex, subunit 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PALMD | palmdelphin |
| PDE8B | phosphodiesterase 8B |
| PLA2G15 | phospholipase A2, group XV |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PRR15L | proline rich 15-like |
| RAI2 | retinoic acid induced 2 |
| RGS19 | regulator of G-protein signaling 19 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM121 | transmembrane protein 121 |
| TMEM132A | transmembrane protein 132A |
| TMEM8B | transmembrane protein 8B |
| ZNF230 | zinc finger protein 230 |
| ZNF239 | zinc finger protein 239 |
| ZNF408 | zinc finger protein 408 |
| ZNF492 | zinc finger protein 492 |
| ZNF770 | zinc finger protein 770 |
| ZNF813 | zinc finger protein 813 |